A5013017406- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Microbial Inactivation Methods
- Cardiovascular Syncope and Autonomic Disorders
- Ocular and Laser Science Research
- Electrostatic Discharge in Electronics
University of Split
2020-2024
Klinički Bolnički Centar Split
2022-2024
University Hospital Centre Zagreb
2024
This study sought to determine whether durable pulmonary vein isolation (PVI) using pulsed field ablation (PFA) translates freedom from atrial fibrillation recurrence without an increase in adverse events.PFA is a nonthermal ablative modality that, preclinical studies, able preferentially ablate myocardial tissue with minimal effect on surrounding tissues. Herein, we present 1-year clinical outcomes of PFA.In 3 multicenter studies (IMPULSE [A Safety and Feasibility Study the IOWA Approach...
Unlike for paroxysmal atrial fibrillation (AF), pulmonary vein isolation (PVI) alone is considered insufficient many patients with persistent AF. Adjunctive ablation of the left posterior wall (LAPW) may improve outcomes, but limited by both difficulty achieving lesion durability and concerns damage to esophagus-situated behind LAPW.This study sought assess safety pulsed field (PFA) PVI LAPW in AF.PersAFOne a single-arm evaluating biphasic, bipolar PFA using multispline catheter under...
Pulsed field ablation (PFA) has emerged as a promising alternative to thermal for treatment of atrial fibrillation (AF). We report performance and safety using the CENTAURI™ System (Galvanize Therapeutics) with three commercial, focal catheters.ECLIPSE AF (NCT04523545) was prospective, single-arm, multi-centre study evaluating acute chronic pulmonary vein isolation (PVI) durability CENTAURI in conjunction TactiCath SE, StablePoint, ThermoCool ST catheters. Patients paroxysmal or persistent...
The unique safety profile of pulsed field ablation (PFA) has made pulmonary vein isolation (PVI) + left atrial posterior wall (LAPW) promising for treating persistent fibrillation (PerAF). goal this study was to assess long-term freedom from fibrillation, flutter, and tachycardia (AF/AFL/AT), as well the feasibility LAPW PFA using multipolar, pentaspline Farawave catheter.
Abstract Background/Introduction Pulsed field ablation (PFA) is emerging as a safe and effective alternative energy modality for cardiac ablation. Data have shown that while tissue contact critical PFA, the amount of force less important. Single-shot catheters comparable results to current thermal methods pulmonary vein isolation (PVI), however, are limited anatomical-based strategies ability detect contact. The investigational QuickShot™ large-area focal catheter (Galvanize Therapeutics,...
Abstract Background Focal pulsed field ablation (fPFA) has emerged as a versatile and innovative strategy for ablating atrial tachyarrhythmias (1). The primary objective of this study is to present the short-term safety characteristics, feasibility procedural outcomes fPFA in management organised tachyarrhythmias. This report focuses on commercial use an (PFA) generator, utilized conjunction with commercially available focal, solid-tip catheters, complemented by 3D electro-anatomical mapping...
BACKGROUND: Pulsed field ablation (PFA) is a promising treatment for atrial fibrillation. We report 1-year freedom from arrhythmia outcomes using monopolar PFA delivered through 3 commercial, contact force–sensing focal catheters. METHODS: ECLIPSE AF (NCT04523545) was prospective, single-arm, multicenter study evaluating acute and chronic safety performance the CENTAURI system to deliver with TactiCath SE, StablePoint, ThermoCool ST. Patients paroxysmal or persistent fibrillation underwent...
Abstract Funding Acknowledgements Type of funding sources: None. Background The occurrence endoscopy-detected oesophageal lesions has been reported in patients with atrial fibrillation (AF) after thermal-based pulmonary vein isolation (PVI) even higher risk undergoing ablation the left posterior wall (LAPW) (1). main mechanism injury is thermal, resulting dysmotility, ulceration, perforation, or atrio-oesophageal fistula formation, which are rare but life-threatening sequelae. Pulsed-field...
Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): University Hospital Center Split Background Catheter ablation in persistent (PeAF), and especially long-standing AF (ls-PeAF) patients often requires beyond pulmonary vein isolation (PVI) (1). Adjunctive the left atrial posterior wall (LAPW) may improve outcomes PeAF but has been limited by difficulty achieving lesion durability concerns thermal damage nearby structures. Pulsed field (PFA) is a...