A5057431003- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Neurotransmitter Receptor Influence on Behavior
- MicroRNA in disease regulation
- Fungal and yeast genetics research
- Bipolar Disorder and Treatment
- Genetics and Neurodevelopmental Disorders
- Enzyme Catalysis and Immobilization
- RNA Research and Splicing
- Biochemical and biochemical processes
- Hematopoietic Stem Cell Transplantation
- Software Testing and Debugging Techniques
- Yersinia bacterium, plague, ectoparasites research
- RNA modifications and cancer
- Forensic and Genetic Research
- Adsorption and biosorption for pollutant removal
- Functional Brain Connectivity Studies
- Gene Regulatory Network Analysis
- Viral Infectious Diseases and Gene Expression in Insects
- Lignin and Wood Chemistry
- Agricultural pest management studies
- Immunotherapy and Immune Responses
- Protein Structure and Dynamics
Indian Institute of Technology Kharagpur
2019-2023
KIIT University
2017
Manovikas Kendra Rehabilitation and Research Institute
2005-2013
Maulana Abul Kalam Azad University of Technology, West Bengal
2012-2013
Abstract Attention deficit hyperactivity disorder (ADHD) is a highly disabling, early onset childhood neurobehavioral with higher occurrence in boys as compared to girls. Pharmacological and molecular genetic studies have revealed the influence of dopaminergic serotonergic systems etiology disorder. Monoamine oxidase A (MAOA) mitochondrial enzyme that regulates signals pre‐synaptic region. Polymorphism promoter region MAOA gene, which comprises 30 bp repeats repeat number varying between...
Abstract Attention deficit hyperactivity disorder (ADHD) is a childhood onset neurobehavioral disorder. Several studies worldwide have implicated possible association between ADHD and transmission of different polymorphisms the dopamine D4 receptor gene ( DRD4 ) in ethnic groups. However, this first report on Indian subjects. Association 5′ flanking 120‐bp duplication, exon 1 12‐bp 3 48‐bp variable numbers tandem repeats (VNTR) were analyzed 50 cases. Haplotype‐based haplotype relative risk...
Abstract MicroRNAs (miRNAs) are small endogenous non-coding RNAs of about 22 nt in length that take crucial roles many biological processes. These short regulate the expression mRNAs by binding to their 3′-UTRs or translational repression. Many current studies focus on how mature miRNAs mRNAs, however, very limited knowledge is available regarding transcriptional loci. It known primary (pri-miRs) first transcribed from DNA, followed formation precursor (pre-miRs) endonuclease activity, which...
Abstract Lachancea kluyveri , a weak Crabtree positive yeast, has been extensively studied for its unique URC pyrimidine catabolism pathway. It produces more biomass than Saccharomyces cerevisiae due to the underlying effect and resorts fermentation only in oxygen limiting conditions that renders it as suitable industrial host. The yeast also ethyl acetate major overflow metabolite aerobic conditions. Here, we report first genome-scale metabolic model, iPN730, of L. comprising 1235...
Objective: ADHD is frequently detected in boys though there no established cause. One possibility that genes predisposing to have sexually dimorphic effects. With an aim find out the reason for this male biasness, contribution of 14 functional polymorphisms was investigated subjects. Method: Genomic DNA probands, their parents, and ethnically matched controls subjected analysis single-nucleotide variable number tandem repeats (VNTRs). Results: Case–control revealed significant higher...
Genetic alterations in the dopaminergic system are frequently observed association with attention deficit hyperactivity disorder (ADHD) and a 40 bp variable number of tandem repeats (VNTR) 3'-untranslated region (3'-UTR) dopamine transporter gene (DAT1) has been investigated different populations. Both significant lack the10 repeat allele (10R) DAT1 VNTR have reported. Objective present investigation was to examine this polymorphism ADHD Indian children. Genotypic data obtained from probands...
MicroRNAs (miRNAs) are a class of small noncoding RNAs that known to have critical functions across various biological processes. Simultaneous activities multiple miRNAs can be monitored from their expression profiles under conditions. We often build up coexpression networks such profiles. Unfortunately, due the change experimental setups (or conditions), do change, and consequently, patterns vary. To obtain robust functional relationship between miRNAs, by integrating different in systems...
Abstract Background Lachancea kluyveri , a weak Crabtree positive yeast, has been extensively studied for its unique URC pyrimidine catabolism pathway. It produces more biomass than Saccharomyces cerevisiae due to the underlying effect and resorts optimal fermentation only in oxygen limiting conditions that render it suitable host industrial-scale protein production. Ethyl acetate, an important industrial chemical, demonstrated be major overflow metabolite during aerobic batch cultivation...