This study was conducted as part of an epidemiological survey 126 nonsmokers and 178 smokers, showing primary infertility residing around Kolkata region Eastern India. Their lifestyle history including smoking habits along with semen blood were collected. The examined the association cigarette risk infertility, by determining quality, follicle stimulating hormone (FSH), luteinizing (LH), testosterone levels, androgen receptor (AR)-CAG repeat length in a group smokers compared control (non...

A novel sensor (<bold>HL5</bold>) recognizes sensitively and selectively trivalent metal ions M³⁺ (M = Al, Fe Cr) with prominent enhancement in emission intensities logic gate circuits memory devices living cell imaging application.

A diformyl-<italic>p</italic>-cresol-8-aminoquinoline based probe exhibits dual colorimetric and fluorogenic properties on selective binding towards Mg²⁺and Zn²⁺. This could be made Mg²⁺over Zn²⁺in the presence of TPEN.

A novel <bold>H3SAL-NH</bold> probe exhibits ESIPT from the phenolic OH group to azomethine N atom in excited state. This is blocked presence of Zn²⁺ and Al³⁺ giving turn on fluorescence which useful for imaging live HepG2 cells.

Abstract Attention deficit hyperactivity disorder (ADHD) is a highly disabling, early onset childhood neurobehavioral with higher occurrence in boys as compared to girls. Pharmacological and molecular genetic studies have revealed the influence of dopaminergic serotonergic systems etiology disorder. Monoamine oxidase A (MAOA) mitochondrial enzyme that regulates signals pre‐synaptic region. Polymorphism promoter region MAOA gene, which comprises 30 bp repeats repeat number varying between...

With an increase in the abuse of various oral habitual products India over past few decades; incidence potentially malignant conditions as leukoplakia, submucous fibrosis and squamous cell carcinoma (SCC) rates have also increased. No recent study has been conducted reporting scenario cancer Eastern (specifically Kolkata).The present was at Dr. R. Ahmed Dental College, Kolkata during 2010-2011 to find a possible correlation between effects different habits, age, sex types mucosal lesions...

Early detection and quantification of DNA damage in oral premalignancy or malignancy may help management the disease improve survival rates. The comet assay has been successfully utilised to detect premalignant malignancy. However, due invasive nature collecting blood, it be painful for many unwilling patients. This study compares micronucleus (MN) buccal mucosa cells with peripheral blood a subset habit-induced precancer cancer For this, MN exfoliated epithelial was compared leucocytes...

A new 8-hydroxyquinoline-pyrazole based probe senses Al³⁺and hence Al³⁺–<bold>8Q-NH-Pyz</bold>complex mediated F⁻in a purely aqueous medium.

A 2-hydroxy-5-methyl-benzene-1,3-dicarboxaldehyde di-oxime based turn-on blue emission fluorescent probe was found to recognize both AsO₂⁻ and H₂AsO₄⁻ in a purely aqueous medium intra extra-cellular conditions.

A smart molecule, QT490, containing thiosemicarbazide moiety acts as a highly selective turn-on in vitro NO sensor through the unprecedented NO-induced transformation of to 1,3,4-oxadiazole heterocycle with concomitant release HSNO, thereby eliminating any interference from various endogenous biomolecules including dehydroascorbic acid, ascorbic etc. The kinetic studies reactions between QT490 and provide mechanistic insight into formation HSNO/RSNO reaction H2S/RSH biological system. This...

A pyridine–pyrazole based fluorescence turn-on chemosensor provides access to selective detection of Al³⁺ in solution as well HepG2 living cells.

Abstract— The influence of pH in the range 1.0 to 13.0 on structure sanguinarine has been investigated by spectrophotometric and spectrofluorimetric measurements. data absorption maxima, molar extinction coefficient, fluorescence emission relative intensity quantum yield under various are presented. It is suggested that dependent absorbance property due formation carbinolamine hydroxylation at C‐6 alkaline pH.

A novel rhodamine-3,4-dihydro-2<italic>H</italic>-1,3-benzoxazine conjugate exhibits excellent selectivity towards Fe³⁺both in extra and intracellular conditions.

A novel diformyl-<italic>p</italic>-cresol (<bold>DFC</bold>)–thiosemicarbazide (<bold>TS</bold>) – based turn-on dual sensor that enables to determine, for the first time, stepwise formation constants.

Fluorescent chemosensors with aggregation induced emission enhancement (AIEE) emerge as promising tools in the field of sensing materials. Herein, we report design, synthesis and applicability a Schiff base chemosensor 1-(benzo[1,3]dioxol-4-ylmethylene-hydrazonomethyl)-naphthalen-2-ol (Hbdhn) AIE characteristics that exhibits highly effective selective response towards Zn2+ . The effect Hbdhn was evaluated by means absorption/emission spectra corresponding underlying photophysical mechanisms...

To describe a novel neural network based oral precancer (oral submucous fibrosis; OSF) stage detection method.The wavelet coefficients of transmission electron microscopy images collagen fibres from normal submucosa and OSF tissues were used to choose the feature vector which, in turn, was train artificial network.The trained able classify stages (less advanced advanced) after obtaining image as an input.The results obtained this proposed technique promising suggest that with further...

Context: The detrimental effects of arsenic on female reproductive functions may involve overt oxidative stress. Casein and pea [Pisum sativum Linn. (Fabaceae)] proteins have antioxidant properties.Objective: To investigate the role casein- pea-supplemented high-protein diet (HPD) in utero-ovarian protection from toxicity.Materials methods: Adult Wistar rats were orally gavaged with vehicle (Gr-I) or at 3 ppm/rat/d (Gr-II Gr-III) for 30 consecutive days, when they maintained either regular...

An easy synthesis of magnetic nanoparticles (Fe3O4) is described. Transmission electron microscopy (TEM), atomic force (AFM), dynamic light scattering (DLS) and X-ray diffraction (XRD) have been used to study the well dispersed uniformly spherical nanoparticles. 5-Fluorouracil (5-FU) has successfully loaded onto cytotoxicity studies were performed using a standard MTT assay. The results indicate that 5-fluorouracil-loaded iron are more potent anticancer drugversus5-fluorouracil alone.