Wan‐Hsing Cheng

ORCID: 0000-0003-4924-7429
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About
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Research Areas
  • Plant Molecular Biology Research
  • Plant Stress Responses and Tolerance
  • Bone health and osteoporosis research
  • Plant nutrient uptake and metabolism
  • Photosynthetic Processes and Mechanisms
  • Bone health and treatments
  • Bone Metabolism and Diseases
  • Microbial Metabolites in Food Biotechnology
  • Plant Reproductive Biology
  • Potato Plant Research
  • Dye analysis and toxicity
  • Vitamin D Research Studies
  • Crop Yield and Soil Fertility
  • Plant Gene Expression Analysis
  • Plant tissue culture and regeneration
  • Polysaccharides and Plant Cell Walls
  • Edible Oils Quality and Analysis
  • Foot and Ankle Surgery
  • HIV-related health complications and treatments
  • Menopause: Health Impacts and Treatments
  • Enzyme Production and Characterization
  • Melamine detection and toxicity
  • Biofuel production and bioconversion
  • Plant-Microbe Interactions and Immunity
  • Hip disorders and treatments

Institute of Plant and Microbial Biology, Academia Sinica
2011-2024

National Defense Medical Center
2014-2022

National Taiwan University
1996-2021

Academia Sinica
2002-2011

Tokyo Metropolitan University
2006

Harvard University
2002-2003

National Taiwan University Hospital
1996-2003

Massachusetts General Hospital
2002-2003

Institute of Botany
2002

University of Florida
1974-1999

Glucose modulates many vital processes in photosynthetic plants. Analyses of Arabidopsis glucose insensitive2 (gin2) mutants define the physiological functions a specific hexokinase (HXK1) plant glucose-signaling network. HXK1 coordinates intrinsic signals with extrinsic light intensity. lacking catalytic activity still support various signaling gene expression, cell proliferation, root and inflorescence growth, leaf expansion senescence, thus demonstrating uncoupling from metabolism. The...

10.1126/science.1080585 article EN Science 2003-04-10

Glc has hormone-like functions and controls many vital processes through mostly unknown mechanisms in plants. We report here on the molecular cloning of GLUCOSE INSENSITIVE1 (GIN1) ABSCISIC ACID DEFICIENT2 (ABA2) which encodes a unique Arabidopsis short-chain dehydrogenase/reductase (SDR1) that as link between nutrient signaling plant hormone biosynthesis. SDR1 is related to SDR superfamily members involved retinoid steroid biosynthesis mammals sex determination maize. antagonizes ethylene...

10.1105/tpc.006494 article EN The Plant Cell 2002-10-24

Abscisic acid (ABA) is an important phytohormone that plays a critical role in seed development, dormancy, and stress tolerance. 9-cis-Epoxycarotenoid dioxygenase the key enzyme controlling ABA biosynthesis In this study, we investigated effect of ectopic expression another gene, ABA2 (or GLUCOSE INSENSITIVE 1 [GIN1]) encoding short-chain dehydrogenase/reductase Arabidopsis (Arabidopsis thaliana). We show ABA2-overexpressing transgenic plants with elevated levels exhibited germination delay...

10.1104/pp.106.084103 article EN cc-by PLANT PHYSIOLOGY 2006-12-22

Although abscisic acid (ABA) and ethylene have antagonistic functions in the control of plant growth development, including seed germination early seedling it remains unknown whether a convergent point exists between these two signaling pathways or they operate parallel Arabidopsis thaliana. To elucidate this issue, four mutants, ctr1, ein2, ein3, ein6, were crossed with aba2 (also known as gin1-3) to generate double mutants. Genetic epistasis analysis revealed that all resulting mutants...

10.1007/s11103-009-9509-7 article EN cc-by-nc Plant Molecular Biology 2009-06-09

Many transcription factors (TFs), such as those in the basic helix-loop-helix (bHLH) family, are important for regulating plant growth and responses to abiotic stress. The expression of OsbHLH035 is induced by drought salinity. However, its functional role rice growth, development, salt response still unknown.The bHLH TF a salt-induced gene that primarily expressed germinating seeds seedlings. Stable GFP-fused transgenic plants revealed this protein predominantly localized nucleus. Osbhlh035...

10.1186/s12284-018-0244-z article EN cc-by Rice 2018-09-10

Although the nucleolus involves two major functions: pre-rRNA processing and ribosome biogenesis/assembly, increasing evidence indicates that it also plays important roles in response to abiotic stress. However, possible regulatory mechanisms underlying nucleolar proteins responsive stress are largely unknown. High salinity is one of stresses, which hinders plant growth productivity. Here, genetic screening approach was used identify a salt hypersensitive mutant 9 (sahy9) mutant, known as...

10.1186/s12870-018-1255-z article EN cc-by BMC Plant Biology 2018-03-01

N-Acetylglucosamine (GlcNAc), a fundamental amino sugar moiety, is essential for protein glycosylation, glycolipid, GPI-anchor protein, and cell wall components. Uridine diphosphate-GlcNAc (UDP-GlcNAc), an active form of GlcNAc, synthesized through the hexosamine biosynthesis pathway (HBP). Although HBP highly conserved across organisms, enzymes involved perform subtly distinct functions among microbes, mammals, plants. A complete block normally causes lethality in any life form, reflecting...

10.3389/fpls.2024.1349064 article EN cc-by Frontiers in Plant Science 2024-03-06

The Arabidopsis thaliana T-DNA insertion mutant rh57-1 exhibited hypersensitivity to glucose (Glc) and abscisic acid (ABA). other two rh57 mutants also showed Glc similar rh57-1, strongly suggesting that the Glc-hypersensitive feature of these results from mutation AtRH57. rh57-3 displayed severely impaired seedling growth when grown in concentrations higher than 3%. gene, AtRH57 (At3g09720), was expressed all organs its transcript significantly induced by ABA, high salt. new belongs class...

10.1111/tpj.12371 article EN cc-by-nc The Plant Journal 2013-11-01

We show here that a cell-wall invertase encoded by the Incw 1 gene is regulated at both transcriptional and posttranscriptional levels sugars in heterotrophic cell suspension culture of maize. The two transcripts: 1-S (small) 1-L (large); size variation was attributable to different lengths 3′ untranslated region. Both metabolizable nonmetabolizable induced RNA apparently default. However, only sugars, sucrose d -glucose, were associated with increased steady-state abundance RNA, concomitant...

10.1073/pnas.96.18.10512 article EN Proceedings of the National Academy of Sciences 1999-08-31

Although N-acetylglucosamine-1-P uridylyltransferase (GlcNAc1pUT) that catalyzes the final step of hexosamine biosynthetic pathway and is conserved among, organisms, produces UDP-N-acetylglucosamine (UDP-GlcNAc), an essential sugar moiety involved in protein glycosylation structural polymers, its biological function plants remains unknown. In this study, two GlcNA.UT genes were characterized Arabidopsis thaliana. The single mutants glcna.ut1 glcna.ut2 revealed no obvious phenotype, but their...

10.1093/pcp/pcu127 article EN Plant and Cell Physiology 2014-09-16

Although exogenous ABA-regulated heterophylly has been well documented in multiple plant species, the effect of endogenous ABA and its molecular mechanism remain uncharacterized. In present study, effects on heterophyllous switching were investigated two different lily varieties, Lilium formosanum oriental hybrid 'Casa Blanca'. Seedlings L. formosanum, which have scale-leaf-type growth, displayed low levels both 9-cis-epoxycarotenoid dioxygenase 3 (LfNCED3) transcripts ABA, whereas seedlings...

10.1093/pcp/pcr117 article EN Plant and Cell Physiology 2011-08-24
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