A5101745092- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Curcumin's Biomedical Applications
- Dendrimers and Hyperbranched Polymers
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Diabetes Management and Research
- Nanoparticles: synthesis and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Graphene and Nanomaterials Applications
- Microbial Natural Products and Biosynthesis
- Enzyme Production and Characterization
- Pharmacological Effects of Natural Compounds
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Nanoplatforms for cancer theranostics
- Sepsis Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- melanin and skin pigmentation
- Glycosylation and Glycoproteins Research
- Metal complexes synthesis and properties
- Forensic Toxicology and Drug Analysis
- Wound Healing and Treatments
Hamedan University of Medical Sciences
2024
Pasteur Institute of Iran
2012-2023
Islamic Azad University of Shahreza
2018
Qom Islamic Azad University
2018
Tehran University of Medical Sciences
2018
Shahid Sadoughi University of Medical Sciences and Health Services
2017
Islamic Azad University Pharmaceutical Sciences Branch
2017
Shahid Chamran University of Ahvaz
2017
University of Tehran
2016
Senescence is an important developmental process that leads to the cell death through highly regulated genetically controlled processes in plants. Biotic and abiotic Oxidative stresses can also artificially induce senescence increase production of reactive oxygen species (ROS) specifically chloroplast. One oxidative paraquat induces deviation electron from photosynthesis chain lead more ROS Plants have evolved special adoptive mechanism reallocate nutrient reproductive juvenile organs...
Platinum nanoparticles (PNPs) were synthesized by chemical reduction of potassium hexachloroplatinate (IV) with trisodium citrate under vigorous stirring and addition sodium dodecyl sulfate as stabilizer reagent. Reducing agent was chosen depending on the oxidation reactions potential values materials used in experiment. The aim this study is to investigate effects PNPs different cancer cell lines cytotoxicity nanomaterial. morphology investigated scanning electron microscope (XL30, Philips...
Targeted drug delivery has received considerable attention due to its key role in improving therapeutic efficacy and reducing the side effects of anticancer drugs. Bleomycin (BLM) is an antibiotic with short half-life, low high that limit clinical applications. This study aims evaluate potential folate-targeted liposomal bleomycin (FL-BLM) free-folate form (L-BLM) on two different cancer cell lines including human cervix carcinoma HeLa, breast MCF-7 cells. Furthermore, effect FL-BLM...
Breast cancer is the fifth most common cause of death among women worldwide. Resistance to cisplatin a main challenge in its treatment. Our present aim was prepare nanoniosomated and examine efficacy vitro using BT-20 cell line. Niosome nanoparticles containing were prepared by reverse-phase evaporation characterized dynamic light scattering (DLS), scanning electron microscopy (SEM), spectrophotometry MTT assay. The size zeta potential nanodrug estimated as 489.3 ± 23.66 nm 23.4 2.1 mV,...
Background/aim: This study aimed to investigate the efficacy of pegylated liposomal etoposide nanoparticles (NPs) against T-47D and MCF-7 breast cancer cell lines. Materials methods: Pegylated NPs were prepared by reverse phase evaporation method. The size, size distribution, zeta potential was measured a Zetasizer instrument. cytotoxicity inspected methyl thiazol tetrazolium assay. release pattern drug from vesicles studied dialysis Drug loading encapsulation efficiency (EE) also measured....
Objective: Today, cancer is one the most important challenges in modern medicine. Breast carcinoma type of that treated with cisplatin, a chemotherapy drug. By using liposomal nanocarriers, this study seeks to increase therapeutic efficiency cisplatin. Method: The zeta potential, particle size, and drug-release characteristics nanoliposomal cisplatin were evaluated after it had been synthesized reverse phase evaporation technique. cytotoxicity rate was then assessed T-47D breast cell line....
Cisplatin is a chemotherapeutic agent used for treating various malignancies. The study aimed to prepare pegylated liposomal cisplatin and evaluate its efficacy against human breast cancer cell line MCF-7. Drug-loaded nanoparticles were synthesized by reverse phase evaporation technique. highlighted extensive characterization of in terms nanoparticle morphology, type drug entrapment, retention capability, cytotoxicity effects. size, size distribution, zeta potential nanodrug estimated 142...
Cancer is one of the most important issues in modern medicine and common cause death after cardiovascular diseases many countries. Brain cancer causes among men women, ranking third. Chemotherapeutic drugs that aim to prevent uncontrolled proliferation cells tissues body induce apoptosis tumor are prominent candidates for development. Since cisplatin has an apoptosisinducing role, it widely used as anticancer agent. In this research, toxicity was studied with C6 rat glioma cell lined using...
Purpose: To encapsulate paclitaxel into nanoliposomes, followed by pegylatation, in order to improve its therapeutic index and reduce side effects breast cancer.Methods: In prepare nanoliposomal paclitaxel, varying ratios of phosphatidylcholine, cholesterol were mixed the formulations pegylated with poly-ethylene glycol 2000 (PEG 2000) enhance stability, efficiency, as well solubility. The mean diameter measured Zeta sizer device release from both was determined within 28 h dialysis method....
Background: Cancer is a significant problem in modern medicine, also the most common cause of death after cardiovascular diseases, and need targeted drug release. Although, chemotherapy an important candidate cancer treatment, but it has many side effects on healthy tissues body. Therefore, Nano technology used for specific function, by least damage to normal cells. Materials method: In this study, pharmacological properties PEGylated Nano-niosomal Gingerol was examined. Noisome were...
The aim of this study was evaluation corn steep liquor as an alternative or substitution medium for production desferrioxamine B in streptomyces pilosus. Desferrioxamine is the major siderophore Streptomyces genus are Gram positive and GC (Guanine/Cytosine) rich bacteria that important many antibiotics secondary metabolites. These metabolites get more attention industrial medical fields. used clinically to treat disorders related iron overload pathological deposition human. Corn Steep Liquor...
The aim of this study was optimization culture medium in direction increasing the production rate desferrioxamine B. Streptomycetes are most widely studied and well known genus actinomycete family. usually inhabit soil important decomposers. Streptomyces Gram-positive GC rich bacteria that for many antibiotics secondary metabolites. These metabolites industrial medical fields. Deferoxamines (also as B, desferoxamine DFO-B, DFOA, DFB or desferal) low-molecular-weight, iron-chelating compounds...