Fadiah Ammar Almutairi

ORCID: 0000-0003-4937-6191
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Research Areas
  • Psidium guajava Extracts and Applications
  • Natural Antidiabetic Agents Studies
  • Enzyme Production and Characterization

Qassim University
2020

Abstract In this study, 5-amino-nicotinic acid derivatives ( 1 – 13 ) have been designed and synthesized to evaluate their inhibitory potential against α-amylase α-glucosidase enzymes. The compounds exhibited promising activities. IC 50 values for activity ranged between 12.17 ± 0.14 37.33 0.02 µg/mL SEM while the were 12.01 0.09 38.01 0.12 SEM. particular, 2 4 8 demonstrated significant activities of these was comparable standard acarbose (10.98 0.03 10.79 0.17 SEM, respectively). addition,...

10.1186/s13065-020-00695-1 article EN cc-by BMC Chemistry 2020-07-14
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