A5087265478- Diatoms and Algae Research
- Marine Biology and Environmental Chemistry
- Protist diversity and phylogeny
- Paleontology and Stratigraphy of Fossils
- Estrogen and related hormone effects
- Bone health and treatments
- Polymer Surface Interaction Studies
- Bone Metabolism and Diseases
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
Technische Universität Dresden
2014-2019
Max Planck Society
2012
Max Planck Institute of Molecular Cell Biology and Genetics
2012
Throughout all kingdoms of life, a large number adhesive biomolecules have evolved to allow organisms adhere surfaces underwater. Proteins play an important role in the adhesion numerous marine invertebrates (e.g. mussels, sea stars, urchins) whereas much less is known about biological adhesives from plants, including diatoms. Diatoms are unicellular microalgae that together with bacteria dominate biofilms sunlit habitats. In this study we present first proteomics analyses diatom material...
Diatoms are single-celled eukaryotic microalgae that ubiquitously found in almost all aquatic ecosystems, and characterized by their intricately structured SiO2 (silica)-based cell walls. with a benthic life style capable of attaching to any natural or man-made submerged surface, thus contributing substantially both microbial biofilm communities economic losses through biofouling. Surface attachment diatoms is mediated carbohydrate- protein- based glue, yet no protein involved diatom...
Abstract The intricate, genetically controlled biosilica nano- and micropatterns produced by diatoms are a testimony for biology’s ability to control mineral formation (biomineralization) at the nanoscale regarded as paradigm nanotechnology. Previously, several protein families involved in diatom have been identified, many of them remain tightly associated with final structure. Determining locations biosilica-associated proteins high precision is, therefore expected provide clues their roles...
Background Studies on osteoclasts, the bone resorbing cells, have remained limited due to lack of transgenic mice allowing conditional knockout genes in osteoclasts at any time during development or adulthood. Methodology/Principal Finding We report here generation which specifically express a tamoxifen-inducible Cre recombinase osteoclasts. These mice, generated C57BL/6 and FVB background, fusion recombinase-ERT2 protein whose expression is driven by promoter cathepsin K (CtsK), gene highly...