A5020693869- HIV, Drug Use, Sexual Risk
- Global Maternal and Child Health
- Anesthesia and Sedative Agents
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Anorectal Disease Treatments and Outcomes
- Substance Abuse Treatment and Outcomes
- Nausea and vomiting management
- HIV/AIDS Research and Interventions
- Urinary Bladder and Prostate Research
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Pharmaceutical studies and practices
- Neonatal and fetal brain pathology
- Antimicrobial Resistance in Staphylococcus
- Neonatal Health and Biochemistry
- Anesthesia and Pain Management
- Antibiotic Resistance in Bacteria
- Opioid Use Disorder Treatment
- Infant Development and Preterm Care
- COVID-19 epidemiological studies
- Hepatitis C virus research
- Infection Control in Healthcare
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Water Access
Post Graduate Institute of Medical Education and Research
2019-2025
University of Pittsburgh
2020-2025
Lincolnshire Partnership NHS Foundation Trust
2024
Sawai ManSingh Medical College and Hospital
2024
Yashoda Hospital
2024
Patna Medical College and Hospital
2023
Institute of Post Graduate Medical Education and Research
2022
Sir Ganga Ram Hospital
2018-2021
Bushey Fields Hospital
2021
Novartis (India)
2014-2017
Most hospitals use traditional infection prevention (IP) methods for outbreak detection. We developed the Enhanced Detection System Healthcare-Associated Transmission (EDS-HAT), which combines whole-genome sequencing (WGS) surveillance and machine learning (ML) of electronic health record (EHR) to identify undetected outbreaks responsible transmission routes, respectively.We performed WGS healthcare-associated bacterial pathogens from November 2016 2018. EHR ML was used routes WGS-detected...
Abstract Background Traditional methods of outbreak investigations utilize reactive whole genome sequencing (WGS) to confirm or refute the outbreak. We have implemented WGS surveillance and a machine learning (ML) algorithm for electronic health record (EHR) retrospectively detect previously unidentified outbreaks determine responsible transmission routes. Methods performed identify characterize clusters genetically-related Pseudomonas aeruginosa infections during 24-month period. ML EHR was...
The US opioid overdose epidemic has been a major public health concern in recent decades. There increasing recognition that its etiology is rooted part the social contexts mediate substance use and access; however, reliable statistical measures of influence are lacking literature. We Facebook's connectedness index (SCI) as proxy for real-life networks across diverse spatial regions help quantify connectivity different units. This measure relative probability connections between localities...
Abstract Purpose: Explore the potential role of a social contagion factor opioid use disorder by attempting to replicate exponential rise in overdose mortality rates using agent-based simulation modeling. Methods: We utilized an model built Framework for Reconstructing Epidemiological Dynamics software implement component. This updated was run Allegheny County 21-year period this pilot study. Results: The death rate trend closely replicated adding component our model. Limitations: original...
Whole genome sequencing (WGS) surveillance and electronic health record data mining have the potential to greatly enhance identification control of hospital outbreaks. The objective was develop methods for examining economic value a WGS surveillance-based infection prevention (IP) program compared standard care (SoC).The IP assessed from hospital's perspective using historical outbreaks 2011-2016. We used transmission network estimate incremental cost per averted. number transmissions...
The association between red blood cell (RBC) transfusions and necrotizing enterocolitis (NEC), so-called transfusion-associated NEC (ta-NEC), was first described in 1987. However, further work is needed to confirm a causal relationship, elucidate underlying mechanisms, develop possible strategies for prevention. We performed an extensive literature search the databases PubMed, EMBASE, Scopus.Although multiple retrospective human studies have strongly suggested subsequent occurrence of NEC,...
Omalizumab add-on to standard-of-care therapy has proven be efficacious in severe asthma patients for whom exacerbations cannot controlled otherwise. Moreover, evidence from different healthcare settings suggests reduced resource utilization with omalizumab. Based on these findings, this study aimed assess the cost-effectiveness of addition omalizumab uncontrolled allergic a Brazilian setting.A previously published Markov model was adapted using Brazil-specific unit costs compare and...
To estimate the prevalence of pressure ulcers in hospitalised patients and any underlying or predisposing factors to ulceration.This cross-sectional study took place a university hospital Varanasi, India. A total 445 medical surgical wards were examined single day for number, site grade ulcers. Haemoglobin, serum albumin blood sugar levels with recorded.The was high (4.94%). Anaemia, malnutrition diabetes important risk factors, while morbidity due long-stay wards, such as neurology,...
ABSTRACT Background Current methods are insufficient alone for outbreak detection in hospitals. Real-time genomic surveillance using offers the potential to detect otherwise unidentified outbreaks. We initiated and evaluated Enhanced Detection System Healthcare-associated Transmission (EDS-HAT), a real-time program mitigation. Methods This study was conducted at UPMC Presbyterian Hospital from November 2021 October 2023. Whole genome sequencing (WGS) performed weekly on healthcare-associated...
To implement Treat All in India, 46 antiretroviral therapy (ART) centers two states supported by the Presidentâs Emergency Plan for AIDS Relief attempted to contact 25,007 persons enrolled HIV care but not receiving ART; 9,898 (40%) subsequently initiated ART over a 14-month period. Among those initiating ART, 6,315 (64%) began after being reached, including 1,635 (17%) who had been lost follow-up.
Abstract We describe the outcome and management of an unusual interesting case delayed post‐traumatic prostatorectal fistula in a 40‐year‐old man. The was repaired successfully via transperineal access without rectal or sphincteric transgression. found surgical approach simple, effective useful approaching region for rectourinary fistulas. is should be considered such select cases. our technique that may beneficial to many urologists.
Aims To improve the quality of care received by service users Electroconvulsive Therapy (ECT) treatment in Lincolnshire Partnership Foundation Trust (LPFT) measuring compliance local ECT clinic accordance with National Institute clinical excellence guidance and accreditation services standards. Methods Pre-audit work up includes consultations lead stake holders to ensure ethical governance standard are met. This audit is conducted permission trust safety team. Sample population identified...
<title>Abstract</title> The US opioid overdose epidemic has been a major public health concern in recent decades. There increasing recognition that its etiology is rooted part the social contexts mediate substance use and access; however, reliable statistical measures of influence are lacking literature. We Facebook’s connectedness index (SCI) as proxy for real-life networks across diverse spatial regions help quantify connectivity different units. This measure relative probability...
Abstract Dysplasia epiphysealis hemimelica (DEH), also known as Trevor’s disease, is a rare disease which skeletal developmental disorder characterized by asymmetrical growth of epiphyseal cartilage. It most frequently affects the ankle joint. Surgical treatment with complete resection recommended before irreversible joint damage and deformity occurs. Multiple surgeries may be required if resected at an early age because recurrences are common until maturity. We present case DEH anteromedial...
Objective: Lower doses of epidural opioids can achieve post-operative analgesia for infraumbilical surgeries. A study was conducted to compare the efficacy butorphanol and fentanyl analgesia, onset, duration, side effects in Methods: on 80 adult patients, both male female, aged between 20 60 years, having American Society Anesthesiologists Physical Status I II, who were undergoing lower abdominal limb surgeries under anesthesia. The patients randomly divided into two groups: Group B. Both...
The US opioid overdose epidemic has been a major public health concern in recent decades. There increasing recognition that its etiology is rooted part the social contexts mediate substance use and access; however, reliable statistical measures of influence are lacking literature. We Facebook's connectedness index (SCI) as proxy for real-life networks across diverse spatial regions help quantify connectivity different units. This measure relative probability connections between localities...