A5054596269- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Respiratory viral infections research
- Infection Control and Ventilation
- Gastrointestinal disorders and treatments
- Virus-based gene therapy research
- Hepatitis Viruses Studies and Epidemiology
- Respiratory Support and Mechanisms
- Congenital Anomalies and Fetal Surgery
- Congenital Diaphragmatic Hernia Studies
Sapporo Medical University
2021-2024
Miwa Hospital
2023
Many reports have reported a reduction in respiratory infectious diseases and gastroenteritis immediately after the coronavirus disease 2019 (COVID-19) pandemic, but data continuing into 2022 are very limited. We sought to understand current situation of various among children Japan as July improve public health post-COVID-19 era.We collected on hospitalized with 18 hospitals from June 2022.In total, 3417 patients were during study period. Respiratory syncytial virus decreased drastically...
Since 2013, equine-like G3 rotavirus (eG3) strains have been detected throughout the world, including in Japan, and were found to be dominant some countries. In 2016, first eG3 outbreak Japan occurred Tomakomai, Hokkaido prefecture, became other areas following year. There no significant differences clinical characteristics of non-eG3 infections. The across 2 years from 2016 2017 had DS-1-like constellations (i.e. G3-P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2), genes highly conserved (97.5-100 %). One...
Abstract Following the coronavirus disease 2019 (COVID‐19) outbreak in February 2020, incidences of various infectious diseases decreased notably Hokkaido Prefecture, Japan. However, Japan began gradually easing COVID‐19 infection control measures 2022. Here, we conducted a survey children hospitalized with human metapneumovirus (hMPV), influenza A and B, respiratory syncytial virus infections 18 hospitals across Japan, spanning from July to June 2023. From March 2020 2022 (28 months), only...
Noroviruses (NoVs) are major causes of acute viral gastroenteritis at all ages worldwide. The molecular epidemiology sporadic cases remains poorly understood, especially in adults. Additionally, no studies have analyzed the transmission route gastroenteritis. In this study, we investigated very mild NoV adults (medical staff) who do not visit outpatient clinic and child outpatients. We also evaluated genotype differences between children possible routes during 5 years. number positives were...
To analyse the epidemiology of intussusception in Hokkaido Prefecture, Japan during a 10-year period spanning introduction rotavirus (RV) vaccine (2007-2016).Using standard questionnaire, retrospective surveillance was conducted across 17 hospitals with paediatric beds Prefecture. We compared data between pre-vaccine era (2007-2011) and post-vaccine (2012-2016).In total, 208 110 cases were pre- eras, respectively. A significant reduction incidence children aged <1 year observed from to...
Group A rotaviruses (RVAs) infect a wide variety of mammalian and avian species. Animals act as potential reservoir to RVA human infections by direct virion transmission or contributing genes reassortants. Here, we report the molecular characterization rare strain Ni17-46 with genotype G15P[14], isolated in Japan 2017 during rotavirus surveillance paediatric outpatient clinic. The genome constellation this was G15-P[14]-I2-R2-C2-M2-A13-N2-T9-E2-H3. This is first an G15 humans, sequencing...
In the 2010s, several unusual rotavirus strains emerged, causing epidemics worldwide. This study reports a comprehensive molecular epidemiological of rotaviruses in Japan based on full-genome analysis. From 2014 to 2019, total 489 rotavirus-positive stool specimens were identified, and associated viral genomes analyzed by next-generation sequencing. The genotype constellations those classified into nine patterns (G1P[8] (Wa), G1P[8]-E2, G1P[8] (DS-1), G2P[4] G3P[8] G8P[8] G9P[8] G9P[8]-E2)....
Abstract The group A rotavirus (RVA) G3P[9] is a rare genotype isolated in humans and cats. We only one strain RVA/Human-wt/JPN/R11-035/2014/G3P[9] among 487 stool samples our surveillance of children with gastroenteritis Japan, during 2014–2015. R11-035 was from 2 year old girl presenting vomiting diarrhea who had daily contact She type histo-blood antigen, which reported to be related human P[9] infection. Full genome sequencing revealed that the AU-1-like constellations, except for NSP3...