Yu-Jen Chen

ORCID: 0000-0003-4960-3702
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About
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Research Areas
  • Advanced DC-DC Converters
  • Silicon Carbide Semiconductor Technologies
  • GaN-based semiconductor devices and materials
  • Electrostatic Discharge in Electronics
  • Electronic Packaging and Soldering Technologies
  • Advanced Radiotherapy Techniques
  • Multilevel Inverters and Converters
  • Impact of Light on Environment and Health
  • Wind and Air Flow Studies
  • Thin-Film Transistor Technologies
  • Photorefractive and Nonlinear Optics
  • Wind Energy Research and Development
  • Microwave Engineering and Waveguides
  • Radio Frequency Integrated Circuit Design
  • Photonic and Optical Devices
  • Semiconductor materials and devices
  • Semiconductor Lasers and Optical Devices
  • 3D IC and TSV technologies
  • Advanced Fiber Laser Technologies
  • Nonlinear Optical Materials Studies
  • Advancements in Semiconductor Devices and Circuit Design
  • Gastric Cancer Management and Outcomes
  • Radiation Therapy and Dosimetry
  • Electromagnetic Compatibility and Noise Suppression
  • Technology and Data Analysis

National Yunlin University of Science and Technology
2024

National Taiwan Ocean University
2024

Lunghwa University of Science and Technology
2024

Feng Chia University
2024

National Cheng Kung University
2007-2023

University of Cincinnati
2023

Industrial Technology Research Institute
2018-2022

National Yang Ming Chiao Tung University
2011-2020

Mackay Memorial Hospital
2006-2020

China Medical University
2020

An efficient driver circuit is proposed for light-emitting-diode (LED) lamps with a dimming feature. The consists of flyback converter in series the dc-link. By processing partial power current regulation, loss produced by conversion can be diminished. feature accomplished means amplitude modulation (AM) or double pulse-width (DPWM). detailed operation stages and analysis are provided. A laboratory designed 45 W LED lamp. Experimental results demonstrate that high efficiency achieved, even...

10.1109/tpel.2012.2183892 article EN IEEE Transactions on Power Electronics 2012-01-13

Adjuvant 5-fluorouracil (5-FU)-based chemotherapy, including FOLFOX (5-FU, leucovorin, and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis remains a common adverse effect which no effective preventive strategies are available. To develop convenient novel way to alleviate mucositis, we investigated the of Lactobacillus casei variety rhamnosus (Lcr35) on FOLFOX-induced mucosal injury. BALB/c mice subcutaneously injected with syngeneic CT26 adenocarcinoma cells...

10.3389/fmicb.2018.00983 article EN cc-by Frontiers in Microbiology 2018-05-15

This paper proposes a twin-buck converter with zero-voltage transition (ZVT). The comprises two identical buck conversion units employing power MOSFETs as the active switches an interleaved inductor. ZVT is accomplished by resonating currents between inductor and parasitic capacitances of MOSFETs. detailed circuit operations analysis are provided. A laboratory rated at 300 W designed tested. Experimental results show that switching losses can be effectively reduced switches, accompanied...

10.1109/tie.2010.2069072 article EN IEEE Transactions on Industrial Electronics 2010-08-24

In this article, a high-power-density off-line light-emitting diode (LED) driver is proposed. The proposed ac-dc the novel integrated buck and boost converter (IBBC). Besides high-power-density, shows high power factor (PF), low total harmonic distortion (THD). IBBC two-stage that features just one controlled switch, which leads to PF THD operation ensuring efficiency, size cost reduction. Moreover, switch current minimized as it conducts higher of or converter, but not addition both in...

10.1109/tpel.2020.2993796 article EN IEEE Transactions on Power Electronics 2020-05-11

To review our experience and evaluate treatment planning using intensity-modulated radiotherapy (IMRT) helical tomotherapy (HT) for the of elderly patients with bladder cancer.From November 2006 through 2009, we enrolled 19 histologically confirmed cancer, 9 in IMRT 10 HT group. The received 64.8 Gy to or without concurrent chemotherapy. Conventional 4-field "box" pelvic radiation therapy (2DRT) plans were generated comparison.The median patient age was 80 years old (range, 65-90 old)....

10.1186/1748-717x-6-75 article EN cc-by Radiation Oncology 2011-06-16

The traditional three-layered metal-dielectric-metal Fabry-Perot filter is developed as a new metal-dielectric multilayered band-pass filter. Our design method allows metal and dielectric films to be alternatively arranged achieve narrow high transmission peak the height remains unchanged for any number of in multilayer. Furthermore, equivalent refractive index subwavelength multilayer could negative real at passband such metamaterial exhibits stronger figure merit than previous result. By...

10.1364/oe.23.033008 article EN cc-by Optics Express 2015-12-14

The present work is to design a passive pitch-control mechanism for small horizontal axis wind turbine (HAWT) generate stable power at high speeds. uses disk pulley as an actuator passively adjust the pitch angle of blades by centrifugal force. For this design, aerodynamic braking caused adjustment angles As marked advantage, does not require mechanical brakes that would incur electrical burn-out and structural failure under speed rotation. This can ensure survival generator in sever...

10.3390/en9050353 article EN cc-by Energies 2016-05-07

Concurrent chemoradiation with 5-fluorouracil (5-FU) is widely accepted for cancer treatment. However, the interactions between radiation and 5-FU remain unclear. Here, we evaluated influence of local irradiation on pharmacokinetics in rats. The single-fraction was delivered to whole pelvic fields Sprague-Dawley rats after computerized tomography-based planning. at 100 mg/kg prescribed 24 hours radiation. A high-performance liquid chromatography system used measure blood. Matrix...

10.1371/journal.pone.0021000 article EN cc-by PLoS ONE 2011-06-09

Lymphangiogenesis is an important biological process associated with cancer metastasis. The development of new drugs that block lymphangiogenesis represents a promising therapeutic strategy. Marine fungus-derived compound phomaketide A, isolated from the fermented broth Phoma sp. NTOU4195, has been reported to exhibit anti-angiogenic and anti-inflammatory effects. However, its anti-lymphangiogenic activity not clarified date. In this study, we showed A inhibited cell growth, migration, tube...

10.3390/md17040215 article EN cc-by Marine Drugs 2019-04-06

A high efficiency driver is proposed for the high-brightness white LED lamp. The consists of a dc power source in series with current regulator. regulation accomplished by partially processing from source. dimming feature lamp can be made regulating current. detailed circuit operation stages and analysis are provided. laboratory designed an which composed eight LEDs. Experimental results demonstrate that achieved even at dimmed power.

10.1109/tencon.2010.5685986 article EN 2010-11-01

A modified forward power factor correction (PFC) converter for light-emitting-diode (LED) lighting applications is proposed in this paper.The circuit topology an integration of a and flyback with multi-windings transformer.The operated as auxiliary voltage source (AVS) connected series the rectified ac grid to achieve low harmonic current distortion high factor.The magnetizing inductance energy recycled charge capacitor AVS.The commonly used constant on-time control primary side regulation...

10.1109/ojpel.2022.3217455 article EN cc-by-nc-nd IEEE Open Journal of Power Electronics 2022-01-01

The effect of dispersing multiwalled carbon nanotubes (MWCNTs) and graphene nanoplatelets (GNPs) in the matrix on low-velocity impact resistance post-impact residual tensile strength fiber reinforced epoxy composite laminates has been experimentally analyzed this study. specimens with by different nanoparticle types various concentrations (0.1, 0.3, 0.5 wt.%) were prepared impacted. quasi-static fatigue tests performed configurations to study influence aforementioned factors damage...

10.3390/polym16243589 article EN Polymers 2024-12-22

This investigation proposes a Fresnel liquid crystal (LC) lens with high diffraction efficiency and low driving voltage. A zone electrode was fabricated on glass plate. zone-distributed electric field in the LC cell induced by proper voltage, yielding concentric structure of LCs as phase lens. remarkable ~39%, close to theoretical limit 40.5%, detected when probed using polarized incident beam wavelength 632.8 nm. The demonstrated depend sensitively applied most suitable voltage 0.9 V. study...

10.1364/ao.48.002094 article EN Applied Optics 2009-04-01

We have proposed and demonstrated a holographic security storage system that is implemented with shift multiplexing technique. The function of this achieved by using microdiffuser (MD) for random phase encoding the reference beams. apparatus in offers an additional flexible during recording processes. can generate memory or nonsecurity via MD not. capacity average signal-to-noise value are 16 bits/μm(2) 3.5, respectively. Lateral shifting selectivity theoretically analyzed experimentally...

10.1364/ao.51.001297 article EN Applied Optics 2012-03-15

We aimed to evaluate the expression levels of tumor suppressor WOX1 in nervous system tumors and its co-expression with p53 neurofibromatosis type 2/merlin (NF2) gene products.Immunohistochemistry, western blotting situ hybridization were used for protein WWOX mRNA expression. Immunofluorescence electron microscopical immunohistochemistry performed colocalization products.WOX1 is low normal cortical neurons, mainly on axon fibers, whereas there moderate high immunoreactivity cytosol nuclei...

10.3233/acp-140087 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2013-01-01

10.1007/s40684-019-00141-1 article EN International Journal of Precision Engineering and Manufacturing-Green Technology 2019-07-23

A high efficiency driver circuit is proposed for Light Emitting Diode (LED) lamps with dimming feature. The consists of a fly-back converter in series the dc-link. By processing partial power conversion current regulation, overall achievable. feature can be accomplished by means linear regulation or double pulse-width modulation (PWM) control scheme. Test results from an exemplar design 45 W LED lamp demonstrate that efficiency.

10.1109/iciea.2011.5975982 article EN 2011-06-01

Background: The effects of radiotherapy (RT) on the pharmacokinetics (PK) 5-FU and 5-fluoro-5,6-dihydro-uracil (5-FDHU) were investigated by animal experiments. Methods: Whole-pelvis RT with 0.5 2 Gy was delivered to Sprague–Dawley rats. at 100 mg/kg intravenously infused 24 hours after radiation. 5-FDHU in plasma bile system calculated. Results: areas under concentration versus time curve (AUC) reduced local irradiation 23.7% (P < 0.001) 35.3% 0.001). AUCs also 21.4% 51.5% Irradiation...

10.3389/fphar.2020.00141 article EN cc-by Frontiers in Pharmacology 2020-02-26

The origins of vertical phase separation and their implication on the device efficiency poly(3-hexylthiophene):[6,6]-phenyl C61-butyric acid methyl ester (P3HT:PCBM) based solar cells, with both regular inverted structures, were investigated. We found that light irradiation filtration processes during fabrications are two key steps induce in active layers. Upon irradiation, devices structures exhibit improved power conversion efficiency, whereas show degradation. spun cast filtered P3HT:PCBM...

10.7567/jjap.53.041601 article EN Japanese Journal of Applied Physics 2014-03-07

A dimmable light-emitting-diode (LED) driver circuit with partial power regulation is proposed in this paper. string of LEDs driven by a dc source series flyback converter. The LED current regulated the converter processing only fractional while major directly supplied from source. To dim pulsed constant amplitude, operated double pulse-width modulation (DPWM). Experimental results on laboratory designed for 48 W lamp have demonstrated excellent efficiency approach.

10.1109/iecon.2015.7392177 article EN 2015-11-01
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