About
Contact & Profiles
A5068176034
Research Areas
- Liver physiology and pathology
- Liver Disease Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Cancer Cells and Metastasis
- Spectroscopy Techniques in Biomedical and Chemical Research
- CAR-T cell therapy research
- Liver Diseases and Immunity
- Immune Cell Function and Interaction
- 3D Printing in Biomedical Research
Vrije Universiteit Brussel
2021-2024
10.1016/j.jhepr.2024.101223
article
EN
cc-by-nc-nd
JHEP Reports
2024-09-20
Local delivery of mRNA-based immunotherapy offers a promising avenue as it enables the production specific immunomodulatory proteins that can stimulate immune system to recognize and eliminate cancer cells while limiting systemic exposure toxicities. Here, we develop employ lipid-based nanoparticles (LNPs) intratumorally deliver an mRNA mixture encoding cytokines interleukin (IL)−21 IL-7 immunostimulatory molecule 4-1BB ligand (Triplet LNP). IL-21 synergy with 4-1BBL leads profound increase...
10.1038/s41467-024-54877-9
article
EN
cc-by-nc-nd
Nature Communications
2024-12-05
10.1016/s0168-8278(24)01374-6
article
EN
Journal of Hepatology
2024-06-01
10.1117/12.3016384
article
EN
2024-06-20
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