Metasurfaces have promised great possibilities in full control of the electromagnetic wavefront by spatially manipulating phase characteristics across interface. Here, we report a scheme to realize broadband backward scattering reduction through diffusion-like microwave reflection utilizing flexible indium-tin-oxide (ITO)-based ultrathin coding metasurface (less than 0.1 wavelength thick) with high optical transparence. The is caused destructive interference scattered far-field wave, which...

Abstract Ultrathin metasurface compromising various sub-wavelength meta-particles offers promising advantages in controlling electromagnetic wave by spatially manipulating the wavefront characteristics across interface. The recently proposed digital coding could even simplify design and optimization procedures due to digitalization of meta-particle geometry. However, current attempts implement still utilize several structural obtain certain responses, requiring time-consuming especially...

Abstract Background Chromosomal instability (CIN), a hallmark of cancer, is commonly linked to poor prognosis in high‐grade prostate cancer (PCa). Paradoxically, excessively high levels CIN may impair cell viability. Consequently, understanding how tumours adapt critical for identifying novel therapeutic targets. Methods Bioinformatic analyses were conducted identify genes overexpressed PCa tissues using The Cancer Genome Atlas (TCGA) and GEO datasets. Western blotting immunohistochemistry...

The asymmetric transmission of electromagnetic (EM) wave can be fully manipulated by chiral metamaterials, but little achieve real-time and high efficient tunability due to challenges in practically deployable solutions. Here, we proposed a new scheme for flexibly dynamically controlling the EM at microwave frequencies using planar metamaterial deep subwavelength thickness incorporated with active components PIN diodes. linearly polarized exhibits efficiency pronounced continuous controlled...

The cotton bollworm Helicoverpa armigera is a worldwide insect pest with the ability to develop resistance many insecticides. Indoxacarb, sodium channel blocker, an important insecticide that used control H. armigera. Cross-resistance, metabolic mechanisms and life history traits were established for indoxacarb-selected (IND-SEL) population of armigera.After 11 generations selection, susceptibility indoxacarb was decreased by 4.43-fold estimated realized heritability (h2 ) only 0.072....

Purpose: The purpose of this study was to investigate the therapeutic effect perillaldehyde (PAE) on Aspergillus fumigatus (A. fumigatus) keratitis. Methods: Human corneal epithelial cells (HCECs) were pretreated with PAE and stimulated A. mycelium. C57BL/6 mice infected treated or without 1 day after infection. Clinical scores, PCR, ELISA, Western blotting used detect expression pro-inflammatory mediators, dendritic cell-associated c-type lectin-1 (Dectin-1), nuclear factor...

Hinokitiol (β-thujaplicin) is an important component of the essential oil extracted from Chamaecyparis obtuse , which prevents decay and decomposition temple shrine buildings in Japan. Hinokiol has been shown to have a detrimental effect on various fungi such as Candida albicans saprophytic fungi. However how hinokitiol works against Aspergillus fumigatus ( A. ) not claimed. This study aims investigate adverse effects disruption cell wall membrane explore possible potential mechanisms or...

Abstract BACKGROUND: Cycloxaprid with cis ‐configuration is a novel neonicotinoid insecticide, developed in China, that has good industrialisation prospects for its high activity against imidacloprid‐resistant pests. Studies were carried out to investigate the biological of cycloxaprid and effect on feeding behaviour Sitobion avenae . RESULTS: The results demonstrated had contact root‐systemic activity. electrical penetration graph (EPG) revealed significantly increased total time...

Aphis gossypii Glover (Hemiptera: Aphididae) is a key pest in cotton crops, notably owing to its increasing resistance commonly used pesticides. Such prompts for the development of integrated management (IPM) programs that include novel pesticides being effective against aphid. In present study, we assessed lethal and sublethal effects cycloxaprid, chiral neonicotinoid pesticide developed China, on A. gossypii. The concentration at 50% (LC50 ) value cycloxaprid was estimated, using dipping...

Abstract A single, free-running, dual-wavelength mode-locked, erbium-doped fibre laser was exploited to measure the absolute frequency of continuous-wave terahertz (CW-THz) radiation in real time using dual THz combs photo-carriers (dual PC-THz combs). Two independent mode-locked beams with different wavelengths and repetition frequencies were generated from this used generate having spacings photoconductive antennae. Based on combs, CW-THz determined a relative precision 1.2 × 10 −9...

The present study aimed to investigate the mechanism underlying sulforaphane-mediated epigenetic regulation of nuclear factor-erythroid derived 2-like 2 (Nrf2) expression in human colon cancer. Proteins were extracted from normal Caco-2 cells using sulforaphane and 5-aza-2'-deoxycytidine (5-Aza) combined with trichostatin A (TSA). mRNA protein levels activity DNA methyltransferase 1 (DNMT1) determined. Methylation-specific polymerase chain reaction bisulfite genomic sequencing also used...

UDP-glycosyltransferases (UGTs) are major phase II enzymes involved in the metabolic detoxification of xenobiotics. In this study, two UGT-inhibitors, 5-nitrouracil and sulfinpyrazone, significantly increased sulfoxaflor toxicity against sulfoxaflor-resistant (Sul-R) Aphis gossypii, whereas there were no synergistic effects susceptible (Sus) A. gossypii. The activity UGTs Sul-R strain was higher (1.35-fold) than that Sus strain. Further, gene expression determination demonstrated 11 23 UGT...

Abstract BACKGROUND To understand the ongoing resistance of cotton bollworm, Helicoverpa armigera , sensitivity five field populations to commonly used insecticides, indoxacarb, abamectin, methoxyfenozide, chlorfenapyr, chlorantraniliprole, spinetoram, lambda‐cyhalothrin, carbosulfan, metaflumizone, chlorpyrifos, and flufenoxuron, were evaluated. Furthermore, biochemical molecular mechanisms field‐evolved in H. also investigated. RESULTS Five showed moderate carbosulfan lambda‐cyhalothrin....

Abstract BACKGROUND Two‐spotted spider mite (TSSM), Tetranychus urticae Koch, is one of the most serious pests agricultural crops. Broflanilide exhibits high lethality against various and has been marketed worldwide under Vedira Tenebenal brands in 2020. Nevertheless, little information reported about its effects on mites. RESULTS displayed higher toxicity to TSSM eggs (24 h LC 50 , 1.015 mg L −1 ) adult females 2.062 than commercial acaricides, including cyflumetofen, bifenazate,...

In this study, we applied laser capture microdissection and a proteomic approach to identify novel nasopharyngeal carcinoma (NPC) biomarkers. Proteins from pooled microdissected NPC normal epithelial tissues (NNET) were separated by two-dimensional gel electrophoresis, differential proteins identified mass spectrometry. Expression of the protein cathepsin D in above two as well four cell lines was determined Western blotting. Next, siRNA used inhibit expression highly metastatic line 5−8F...

Cycloxaprid is a novel cis-configuration neonicotinoid insecticide that effective against wide range of insect pests, including those are resistant to conventional neonicotinoids. In this study, life table parameters were applied estimate the cycloxaprid-induced sublethal effects on Aphis gossypii. The results indicated LC20 (0.81 mg a.i. L-1) cycloxaprid significantly decreased pre-oviposition period in first-progeny adults. Additionally, expectancy F1 generation adults was reduced....

Endometrial cancer is a life‑threatening malignancy that affects women all over the world, and it has an increasing incidence. MicroRNAs (miRNAs/miRs) have been reported to be involved in cellular activities endometrial cancer. The present study aimed examine effects of miR‑183‑5p on epithelial‑mesenchymal transition (EMT), proliferation, invasion, migration apoptosis human cells by targeting Ezrin. Primary tissues adjacent normal were obtained for investigation. protein expression Ezrin was...

This study aimed to determine the mechanisms of antifungal and anti-inflammation effects pseudolaric acid B (PAB) on Aspergillus fumigatus (A. fumigatus) keratitis. In vitro MIC assay crystal violet staining were conducted evaluate efficacy PAB against A. fumigatus. inhibited growth formation fungal biofilms in a dose-dependent manner. Molecular docking analysis revealed that possesses strong binding properties with Rho1 fumigatus, which is devoted encoding (1,3)-β-d-glucan RT-PCR results...