A5111003331- Influenza Virus Research Studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- vaccines and immunoinformatics approaches
- Machine Learning in Bioinformatics
Ruijin Hospital
2024
Jiading District Central Hospital
2023
Influenza A virus (IAV) causes highly contagious respiratory disease worldwide, so prevention and control of IAV is extremely important. However, overuse neuraminidase inhibitor (NAI) drugs leads to drug resistance. To explore the up-to-date geographical distribution evolution drug-resistant mutations (DRMs) in NA protein IAV, 81,492 near full-length sequences downloaded from NCBI GISAID databases, including 34,481 H1N1 46,622 H3N2, were processed analyzed. Our results showed annual number...
Introduction: Influenza is a severe respiratory viral infection that causes significant morbidity and mortality, due to annual epidemics unpredictable pandemics. With the extensive use of neuraminidase inhibitor (NAI) drugs, influenza B virus has carried different drug-resistant mutations. Thus, this study aimed analyze prevalence mutations virus. Methodology: Near full-length sequences (NA) region all viruses from January 1, 2006, December 31, 2018, were downloaded public databases GISAID...