A5019094739- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Attention Deficit Hyperactivity Disorder
- Infant Development and Preterm Care
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- Health disparities and outcomes
- Child Abuse and Trauma
- Breastfeeding Practices and Influences
- Maternal and Neonatal Healthcare
- Functional Brain Connectivity Studies
- Health, Environment, Cognitive Aging
- Health and Lifestyle Studies
- Genetics and Neurodevelopmental Disorders
- Youth, Drugs, and Violence
- Bipolar Disorder and Treatment
- Smoking Behavior and Cessation
- Homelessness and Social Issues
- Early Childhood Education and Development
- Autism Spectrum Disorder Research
- Congenital Heart Disease Studies
- Food Security and Health in Diverse Populations
- Children's Physical and Motor Development
Universidade Federal de Pelotas
2013-2022
Hospital de Clínicas de Porto Alegre
2013-2016
Universidade Federal do Rio Grande do Sul
2004-2016
Universidade Católica de Pelotas
2016
Universidade de São Paulo
2016
National Council for Scientific and Technological Development
2013-2016
Universidade Federal do ABC
2015
Universidade Federal de Ciências da Saúde de Porto Alegre
2015
Universidade Federal do Rio Grande
2010-2015
University of Bristol
2011
Background A novel approach is explored for improving causal inference in observational studies by comparing cohorts from high-income with low- or middle-income countries (LMIC), where confounding structures differ. This applied to assessing effects of breastfeeding on child blood pressure (BP), body mass index (BMI) and intelligence quotient (IQ). Methods Standardized approaches the structure socio-economic position were British Avon Longitudinal Study Parents Children (ALSPAC) (N ≃ 5000)...
<h3>Importance</h3> The requirement of a childhood onset has always been key criterion for the diagnosis attention-deficit/hyperactivity disorder (ADHD) in adults, but recently this become surrounded by controversy. <h3>Objective</h3> To investigate whether impaired young adults with ADHD symptoms have childhood-onset population-based longitudinal study. <h3>Design, Setting, and Participants</h3> Participants belonged to 1993 Pelotas Birth Cohort Study, including 5249 individuals born...
<h3>Abstract</h3> <b>Objective</b> To examine the effects of early social, anthropometric, and behavioural variables on physical activity in adolescence. <b>Design</b> Prospective birth cohort study. <b>Setting</b> Pelotas, southern Brazil. <b>Participants</b> 4453 adolescents aged 10-12 years participating Pelotas 1993 study (follow-up rate 87.5%). <b>Main outcome measures</b> Sedentary lifestyle (< 300 minutes per week) median score (minutes week). <b>Results</b> The prevalence a...
Few studies have addressed the course and severity of maternal depression its effects on child psychiatric disorders from a longitudinal perspective. This study aimed to identify patterns evaluate whether distinct trajectories predict particular in offspring.Cohort 4231 births followed-up city Pelotas, Brazil. Maternal depressive symptoms were assessed with Edinburgh Postnatal Depression Scale (EPDS) at 3, 12, 24 48 months 6 years after delivery. Psychiatric 6-year-old children evaluated...
The DSM criteria for adult attention-deficit/hyperactivity disorder (ADHD) have not been tested in American Psychiatric Association (APA) field trials either DSM-IV or DSM-5. This study aimed to assess: (a) the prevalence of ADHD according DSM-5 criteria; (b) factor solution that provides best fit symptoms; (c) symptoms with highest predictive value clinical impairment; and (d) symptomatic threshold each dimension (inattention hyperactivity/impulsivity).Trained psychologists evaluated 4000...
This paper describes the main methodological aspects of a cohort study, with emphasis on its recent phases, which may be relevant to investigators planning carry out similar studies. In 1993, population based study was launched in Pelotas, Southern Brazil. All 5,249 newborns delivered city's hospitals were enrolled, and sub-samples visited at ages one, three six months one four years. 2004-5 it possible trace 87.5% age 10-12 Sub-studies are addressing issues related oral health,...
To explore associations of maternal prenatal smoking and child psychological problems determine the role causal intrauterine mechanisms.Maternal were explored in 2 birth cohorts Pelotas, Brazil (n = 509, random subsample), Avon Longitudinal Study Parents Children (ALSPAC) Britain 6735). Four approaches for exploring mechanisms applied: (1) cross-population comparisons between a high-income middle-income country; (2) multiple adjustment socioeconomic parental factors; (3) maternal-paternal as...
Most studies published on the prevalence of psychiatric disorders in children were conducted high-income countries despite fact that nearly 90 % world’s population aged under 18 live low- and middle-income countries. The study aimed to assess among 6 years age, examine distribution by gender socioeconomic status evaluate occurrence comorbidities. 2004 Pelotas Birth Cohort originally comprised 4,231 births from Pelotas, southern Brazil. A total 3,585 (84.7 births) assessed using Development...
Prediction models have become frequent in the medical literature, but most published studies are conducted a single setting. Heterogeneity between development and validation samples has been posited as major obstacle for generalization of models. We aimed to develop multivariable prognostic model using sociodemographic variables easily obtainable from adolescents at age 15 predict depressive disorder diagnosis 18 evaluate its generalizability 2 diverse socioeconomic cultural settings.Data...
Abstract – Objectives: To test whether malocclusion had an impact on adolescents’ appearance satisfaction regardless of other physical aspects. Methods: A cross‐sectional study nested in a birth cohort was carried out Pelotas, Brazil. random sample 900 15‐year‐old adolescents selected. WHO criteria were used to define and questionnaire administered including self‐reported skin colour satisfaction. Dental caries assessed. Height weight measured body mass index calculated. Data concerning...
Attention-deficit/hyperactivity disorder (ADHD) is characterized by persistent symptoms of lack attention, impulsivity and hyperactivity. The association between nutritional exposures ADHD has been investigated some studies have identified adverse effects from higher intake sugar. objective the present study was to evaluate change in sugar consumption 6 11 years age incidence attention-deficit/hyperactivity (ADHD). Pelotas 2004 Birth Cohort Study Brazil. A food frequency questionnaire (FFQ)...
Most children live in low- and middle-income countries (LMICs), many of which have high levels violence. Research high-income (HICs) shows that childhood behaviour problems are important precursors crime Evidence is lacking on whether this also true LMICs. This study examines prevalence rates associations between conduct hyperactivity violence Brazil Britain.
The present study aimed to evaluate the prevalence of psychiatric disorders in early adolescence, examine distribution by maternal and child characteristics occurrence comorbidities.This was a prospective cohort all live births city Pelotas, Brazil, 2004 (n = 4231). A total 3562 subjects were evaluated at 11 years age. Psychiatric assessed using Development Well-Being Assessment. Crude adjusted logistic regression used investigate risk factors for any disorder.According DSM-5 criteria,...
Background: This investigation aimed at examining, through an epidemiological study, the social demographic, family and individual determinants of behaviour problems in preschool children. Method: Six hundred thirty‐four children, age four years, their mothers, belonging to a cohort 5,304 children being followed from birth, took part study. During home visit, child's IQ were examined, as well prevalence maternal psychiatric disorder, quality environment, other factors. Results: The results...
Background: All previous longitudinal community studies assessing the continuity of child behavioral/emotional problems were conducted in developed countries. Method: Six hundred and one children randomly selected from a Brazilian birth cohort evaluated for through mother interview at 4 12 years with same standard procedure – Child Behavior Checklist (CBCL). Results: CBCL Total Problem score presented medium stability ( r = .42) externalizing showing higher more homotypic than internalizing...
The aim of this study is to describe the methodology 2004-2005 follow-up visit 1993 Pelotas (Brazil) birth cohort. All children born in and whose mothers lived city at that time were eligible be enrolled a longitudinal study. Between July 2004 March 2005, all cohort participants sought for visit. Several strategies used help trace members, including census city's schools households municipality. Mortality Information System was monitored order identify deaths among members. Of 5,249 4,452...
Background: The study of gene–environment interactions (G × E) is one the most promising strategies to uncover origins mental disorders. Replication initial findings, however, essential because there a strong possibility publication bias in literature. In addition, scarcity research on topic originated from low‐ and middle‐income countries (LMIC). aim this was replicate G E hypotheses for externalizing problems among adolescents country. Methods: As part Pelotas 1993 Birth Cohort Study,...
Abstract Attention‐Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder with strong genetic component. The glutamate metabotropic receptor genes ( GRM s) have been considered potential candidates for ADHD susceptibility. aim of the present study was to investigate if copy number variants (CNVs) in GRM1 , GRM5 and GRM8 are overrepresented subjects. A total 1038 individuals 1057 subjects without this were investigated. No significant difference CNVs found comparing...
Several efforts have been made to find new genetic risk variants which explain the high heritability of ADHD. At genome level, genes involved in neurodevelopmental pathways were pointed as candidates. CDH13 and CTNNA2 are within GWAS top hits ADHD there emerging notions about their contribution pathophysiology. The main goal this study is test association between SNPs across life cycle subjects with This included 1,136 unrelated cases 946 individuals without No significant an d was observed...
Background Excessive crying in early infancy has been associated with behavioural problems among preschool children from high income countries but studies low and middle are scarce. Methods The 2004 Pelotas Birth Cohort is a population-based study planned to enrol all live births occurring that year comprises 4231 who so far have followed up at 3, 12, 24, 48 72 months of age. Several familial, maternal child characteristics were gathered every follow-up. At the 3-month follow-up, infants...
To date, there have been few studies of DMDD examining the risk factors during gestation and first years life. We assessed perinatal postnatal associated with occurrence disruptive mood dysregulation disorder (DMDD) by 11 age.Prospective longitudinal study. Mothers completed a standardized questionnaire shortly after childbirth. used Development Well-Being Assessment, administered to mothers or legal guardians, identify among 11-year-old subjects. also employed logistic regression perform...
Background : Youth violence is a major global public health problem. Three UK and Swedish studies suggest that low resting heart rate predicts male youth violence, but this has not been tested in other social settings nor for females. Methods A prospective, population-based birth cohort study was conducted Pelotas, Brazil. Heart measured using wrist monitor at ages 11, 15 18 years. Violent crime non-violent were age self-reports official records ( N = 3618). Confounding variables assessed...