A5002050236- Medicinal Plants and Bioactive Compounds
- Chemotherapy-induced organ toxicity mitigation
- Microbial Metabolites in Food Biotechnology
- Aldose Reductase and Taurine
- Pharmacological Effects and Toxicity Studies
- Seaweed-derived Bioactive Compounds
- Chemical Reaction Mechanisms
- Tuberculosis Research and Epidemiology
- MicroRNA in disease regulation
Mahidol University
2024
Thammasat University
2020-2021
Objective: Many studies suggested that fucoidan has anticancer potential. The objective of the present study was to determine cytotoxic effects and mechanism cell death induced by extracted from Fucus vesiculosus on HSC-3 oral squamous carcinoma. Methods: cells were treated with 0, 100, 200, 400 μg/mL fucoidan. Cell viability measured using MTT assay. Apoptosis cycle a flow cytometry-based Chromatin condensation nuclear fragmentation determined Hoechst 33342 staining. Mitochondrial membrane...
The combination treatment is a way to improve the therapeutic strategy of temozolomide (TMZ) -resistant glioblastoma (GBM). Taurine (TAU) has potential inhibit growth in various cancer cells. aim this study was examine combined effects TMZ and TAU on cultured human GBM, U-251 MG cells.The cells were incubated with TMZ, TAU, both ratios. MTT assay performed measure cell viability treatments then synergistic interactions evaluated by Chou-Talalay method. cycle apoptotic properties examined...