Sean W. Chen

ORCID: 0009-0000-2388-9787
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About
Contact & Profiles
Research Areas
  • Cancer Immunotherapy and Biomarkers
  • Neonatal Respiratory Health Research
  • COVID-19 and healthcare impacts
  • Epilepsy research and treatment
  • Viral-associated cancers and disorders
  • Brain Metastases and Treatment
  • Lung Cancer Research Studies
  • Polyomavirus and related diseases
  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • CNS Lymphoma Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Ethics and Legal Issues in Pediatric Healthcare
  • Vaccine Coverage and Hesitancy
  • Phagocytosis and Immune Regulation

City of Hope
2022-2024

Beckman Research Institute
2023

Columbia University Irving Medical Center
2021

Abstract Purpose Primary central nervous system post-transplantation lymphoproliferative disorder (PCNS-PTLD) is a rare but serious complication of hematopoietic stem cell transplantation (HSCT) in patients with severe β-thalassemia. This study aimed to assess the clinical presentation, pathological characteristics, neuroimaging findings, and treatment strategies β-thalassemia who developed PCNS-PTLD compare case series from our transplant center reported cases literature. Methods We...

10.1186/s13244-024-01605-y article EN cc-by Insights into Imaging 2024-02-14

Non-small cell lung cancer (NSCLC) has a high rate of brain metastasis. The purpose this study was to assess the differential distribution metastases from primary NSCLC based on mutation status. Brain MRI scans patients with were retrospectively analyzed. metastatic tumors grouped according status their and neuroimaging features these A total 110 1386 included in study. Gray matter density at tumor center peaked ~0.6 for all mutations. median depths 7.9 mm, 8.7 mm 9.1 EGFR, ALK KRAS groups,...

10.3390/brainsci13071057 article EN cc-by Brain Sciences 2023-07-11

Since the approval of COVID-19 vaccines, their safety and efficacy has been widely demonstrated in patients with cancer. However, there remain reservations regarding vaccination. We aimed to assess genitourinary cancer patients' perceptions vaccines as well barriers influencers decision-making through completion a questionnaire. While vaccine-associated concerns were observed, most cancers willing receive vaccine. Moving forward, differing strategies could be considered enhance patient...

10.1080/07357907.2022.2136683 article EN Cancer Investigation 2022-10-14
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