A5103579816- Rabies epidemiology and control
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Ovarian cancer diagnosis and treatment
- Viral Infections and Immunology Research
- Poxvirus research and outbreaks
- Hepatocellular Carcinoma Treatment and Prognosis
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- Polyomavirus and related diseases
- Male Reproductive Health Studies
- Parasitic infections in humans and animals
- Viral Infections and Vectors
- Lymphoma Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Hepatitis B Virus Studies
- Genetic factors in colorectal cancer
- Bacillus and Francisella bacterial research
- Influenza Virus Research Studies
- Shoulder and Clavicle Injuries
- Uterine Myomas and Treatments
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Cardiovascular Syncope and Autonomic Disorders
- Breast Lesions and Carcinomas
Universidade de São Paulo
2018-2024
Hospital Fernández
2014-2017
Instituto Pasteur
2010-2015
Hospital Garcia de Orta
2014
Secretaria da Saúde
2009-2010
Institut Pasteur
2010
Background. Torquetenovirus (TTV) is a small DNA virus constituting the human virome. High levels of TTV-DNA have been shown to be associated with immunosuppression and inflammatory chronic disorders. Aim. To assess possible association between salivary viral load in patients hospitalised due COVID-19 disease severity. Methods. Saliva samples collected from 176 infected SARS-CoV-2 were used investigate presence by use real-time RT-PCR. Results. The majority male severe COVID-19. Presence was...
Torque teno virus (TTV) has been pointed as an endogenous marker of immune function, the objective this study was to investigate TTV viral load in plasma and saliva cirrhotic individuals correlate it with clinical characteristics.Blood, saliva, data from records laboratory tests were collected 72 patients. Plasma submitted real-time polymerase chain reaction for quantification load.The majority patients presented decompensated cirrhosis (59.7%) 47.2% had alterations white blood series....
To evaluate the humoral immune response to pre-exposure schedule of human rabies vaccination through intradermal and intramuscular routes, as well need for serological monitoring.A randomized controlled intervention study was carried out in São Paulo, Southeastern Brazil, from 2004-2005. There were 149 volunteers, which 127 completed (65 62 intramuscular) underwent evaluation at ten, 90 180 days post-vaccination. Two outcomes considered comparing two routes administration: geometric average...
We present a case of pathologically proven multinodular diffuse hepatic hemangiomatosis (DHH) with no extra-hepatic involvement in 68-year-old male. Cavernous hemangioma is the most common tumor. However, DHH, which characterized by extensive replacement liver parenchyma hemangiomatous lesions, has been rarely reported adults. The etiology and clinical course are not completely understood because its rareness, although diagnosis might be suggested magnetic resonance imaging findings.
Several reports have proposed that the viral load of torque teno virus (TTV) in plasma is a biomarker immune function solid organ transplantation (SOT) and allogeneic hematopoietic stem cell transplantation. Additionally, for latter one, TTV-DNA quantification saliva has also been suggested. to investigate correlation between TTV paired samples patients on kidney was quantified from 71 before short-time after renal-transplantation by real-time PCR. The data obtained 213 showed slight...
In Brazil, various isolates of rabies virus (RABV) show antigenic profiles distinct from those established by the reduced panel eight monoclonal antibodies (MAbs) determined Centers for Disease Control and Prevention (CDC), utilized characterization RABV in Americas. The objective this study was to produce MAbs insectivorous bats with an profile incompatible pre-established one.An isolate species Eptesicus furinalis that showed selected. Hybridomas were produced utilizing popliteal lymph...
OBJETIVO: Avaliar a resposta imune humoral do esquema de pré-exposição da raiva humana realizado pelas vias intramuscular e intradérmica necessidade sorologia controle. MÉTODOS: Estudo intervenção controlado randomizado, em São Paulo, SP, 2004-2005. Foram recrutados 149 voluntários, dos quais 127 (65 62 intramuscular) completaram o vacinação realizaram avaliação dez, 90 180 dias após término vacinação. considerados dois desfechos para comparação entre as duas aplicação: média geométrica...
A raiva é uma zoonose viral que acomete o sistema nervoso central (SNC) de mamíferos, considerada um grave problema saúde pública. Herbívoros (bovinos e equinos) são frequentemente acometidos pela in-fecção após serem atacados por morcegos hematófagos (Desmodus rotundus). técnica imunofluorescência direta (IFD) realizada em tecidos frescos, recomendada Organização Mundial Saúde (OMS), utilizada para diagnóstico da raiva. imuno-histoquímica (IHQ) detectar antígenos fixados, pelo uso...
The aim of this study was to assess whether biochemical, biological, and anthropometric characteristics are related the XbaI polymorphism APOB in obese patients aged 50+, as well verify susceptibility health impairment. This research is a cross-sectional, comparative, analytical with both quantitative qualitative approaches, consisting 21 elderly women 50 years or older who underwent Roux-en-Y- gastric bypass surgery one year ago. Clinical data blood samples were collected 12 months after...
Background: MicroRNAs (miRNAs) of polyomavirus (PyV) are present in several biological fluids and suggested to be relevant viral factors for monitoring its persistence.Aim: To evaluate the effect an immunosuppressive regimen on status PyV-miRNA-5p oral cavity.Materials Methods: The JCPyV, BKPyV, MCPyV miRNA-5p were investigated paired saliva plasma samples obtained from 23 patients before shortly after renal-transplantation by using real-time RT-PCR.Results: Overall, within a short-time...
Os tecomas sao tumores raros do ovario, grupo dos cordoes sexuais, de natureza solida e frequentemente unilaterais. Tem maior incidencia no periodo pos-menopausa normalmente silenciosos. Quando sintomaticos traduzem-se por dor pelvica metrorragia (condicionada pela habitual produtora estrogenios tumor). Podem ser concomitantes a sindrome Meigs e/ou Golin-Goltz associarem-se transformacao benigna ou maligna endometrio. Embora ecografia possa inespecifica neste contexto, uma avaliacao...