A5039086499- Photochromic and Fluorescence Chemistry
- Supramolecular Self-Assembly in Materials
- Lipid Membrane Structure and Behavior
- Photoreceptor and optogenetics research
- Polydiacetylene-based materials and applications
- Crystallization and Solubility Studies
- Synthesis and pharmacology of benzodiazepine derivatives
- X-ray Diffraction in Crystallography
- Molecular Sensors and Ion Detection
- Coordination Chemistry and Organometallics
- Erythrocyte Function and Pathophysiology
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Surface Modification and Superhydrophobicity
- Catalytic C–H Functionalization Methods
- Vascular Malformations Diagnosis and Treatment
- Advanced Sensor and Energy Harvesting Materials
- Adhesion, Friction, and Surface Interactions
- Polymer Science and PVC
- Sphingolipid Metabolism and Signaling
- Hydrogels: synthesis, properties, applications
- Nanocomposite Films for Food Packaging
- Intracranial Aneurysms: Treatment and Complications
- Antimicrobial agents and applications
University of Salerno
2018-2025
In this study, we introduce a novel method for quantifying the mechanical properties of lipid membranes-bending rigidity (κ), Gaussian (κG), and surface tension (γ) using molecular dynamics (MD) simulations. Our approach is applied to membranes incorporating 2-hydroxyoleic acid (2OHOA), synthetic oleic derivative currently under clinical investigation its anticancer properties. 2OHOA modifies plasma membrane composition in cancer cells activates sphingomyelin synthase 1 (SMS1), an enzyme...
Azobenzene photoswitches are fundamental components in contemporary approaches aimed at light-driven control of intelligent materials. Significant endeavors directed towards enhancing the light-triggered reactivity azobenzenes for such applications and obtaining water-soluble molecules able to act as crosslinkers a hydrogel. Here, we report rational design synthesis azobenzene/alginate photoresponsive hydrogels endowed with fast reversible sol–gel transition. We started three cationic (AZOs...
2‐Acetylbenzonitriles have been conveniently synthesized by the oxidation of respective 2‐ethylbenzonitriles, combining in a one‐pot procedure radical bromination and hydrolysis reactions. The obtained ketones reacted under very mild conditions with carbon hetero nucleophiles to give wide range 3,3‐disubstituted isoindolinones yields 80–99 % tandem process consisting an addition step subsequent Dimroth‐type rearrangement. Among tested nucleophiles, water presence catalytic amount KOH allowed...
Azobenzene photoswitches are fundamental components in contemporary approaches aimed at light-driven control of intelligent materials. Significant endeavors directed towards enhancing the light-triggered reactivity azobenzenes for such applications and obtaining water-soluble molecules able to act as crosslinkers a hydrogel. Here, we report rational design synthesis azobenzene/alginate photoresponsive hydrogels endowed with fast reversible sol-gel transition. We started three cationic (AZO...
The study of the cell membrane is an ambitious and arduous objective since its physical state regulated by a series processes that guarantee regular functionality. Among different methods analysis, fluorescence spectroscopy technique election, non-invasive, easy to use. Besides, molecular dynamics analysis (MD) on model membranes provides useful information possibility using new probe, following positioning in membrane, evaluating possible perturbation double layer. In this work, we report...