A5101861442- Metallic Glasses and Amorphous Alloys
- Additive Manufacturing Materials and Processes
- High-Temperature Coating Behaviors
- Nanoplatforms for cancer theranostics
- Advanced Fiber Laser Technologies
- Electromagnetic Effects on Materials
- High Entropy Alloys Studies
- Quantum Mechanics and Non-Hermitian Physics
- Planetary Science and Exploration
- Laser and Thermal Forming Techniques
- Nonlinear Photonic Systems
- Metallurgy and Material Forming
- Quasicrystal Structures and Properties
- Pulsed Power Technology Applications
- Metal Forming Simulation Techniques
- Phase Change Materials Research
- Advanced Surface Polishing Techniques
- interferon and immune responses
- RNA Research and Splicing
- Aluminum Alloys Composites Properties
- Amino Acid Enzymes and Metabolism
- Extracellular vesicles in disease
- Heat Transfer and Optimization
- Intermetallics and Advanced Alloy Properties
- IPv6, Mobility, Handover, Networks, Security
Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025
Harbin Medical University
2024
Beihang University
2023
Suzhou University of Science and Technology
2023
The University of Sydney
2020
Harbin Institute of Technology
2011-2020
Liaoning University of Technology
2015
Dextrorotary (d) peptides, composed of d-amino acids, are hyper-resistant to proteolytic hydrolysis, making them valuable ligands with excellent in vivo stability for radiopharmaceutical development. Multimerization is a well-established strategy enhancing the performance l-peptide-based radiopharmaceuticals. However, effect multimerization on fate d-peptide-based radiopharmaceuticals remains largely unexplored. Here, we synthesized d-peptide DPA, which targets PD-L1, along its dimer (DP2)...
Abstract Background Patients with cold tumors gain limited benefits from immune checkpoint blockade (ICB) therapy owing to low programmed cell death protein ligand 1 (PD‐L1) expression and minimal infiltration. Mild photothermal (PTT) using black phosphorus nanosheets (BPNSs) is a promising approach enhance the efficacy of ICB therapy. However, ensure that BPNS‐based PTT‐enhanced clinically adaptable, noninvasive, bedside‐accessible imaging tool capable monitoring status PD‐L1 imperative. We...
The application of exceptional points in non-Hermitian photonic systems has attracted attention the field ultra-high-sensitivity sensing. However, realization an point (EP) experiments requires precise control multiple parameters sensor, which limits practical applicability EP-enhanced sensors. In this work, surface (ES)-enhanced displacement sensing is experimentally demonstrated a fiber ring resonator to break through restriction. Expanding EPs ES makes system immune fabrication errors and...
The plastic stability of bimetals composed a Ti-based metallic glass composite (MGC) and pure titanium (PT) under tension has been investigated. results reveal that the MGC/PT bimetal is strongly dependent on thickness fraction MGC: when MGC decreases to critical value, homogeneous deformation occurs in bimetals, i.e. strain localization necking effectively suppressed. This unique phenomenon explained using normalized strain-hardening rate, quantitative relationship between rate thereby established.
An exceptional surface (ES) has advantages in improving sensing robustness and enhancing frequency splitting. Typically, the eigenvalue splitting must exceed mode linewidth order to be clearly visible spectrum, which limits precision of ES-based structure. In this paper, a strategy for manipulating spectral line shape an structure is experimentally realized. addition, limit minimum detectable displacement can further reduced by monitoring peak intensity Fano interference shape. The...
The neuroendocrine-immune (NEI) network is fundamental for maintaining body's homeostasis and health. While the roles of microRNAs (miRNAs) transcription factors (TFs) in disease processes are well-established, their synergistic regulation within NEI has yet to be elucidated. In this study, we constructed a background NEI-related miRNA-TF regulatory (NEI-miRTF-N) by integrating signaling molecules (including miRNAs, genes, TFs) identifying feed-forward loops. Our analysis reveals that number...
This paper presents a drilling and coring device for the lunar exploration, which is possibly utilized to acquire regolith with certain depth. The composed of three components: rotary unit, percussive unit penetrating unit. rotary-percussion drill can work in two different operating modes: mode rotary-percussive mode, depending on properties cut object. In relatively loose regolith, rotation penetration make well state. However, once rock encountered process, besides penetration, percussion...
AbstractBased on an Inconel 718 superalloy thick plate bending product with gradient radius (thickness: 12 mm), the accuracy control of hot was studied by finite element method numerical simulation and experimental test. Meanwhile, effects die gap friction coefficients were investigated using Deform‐3D, parameters test have been improved. The results show that radial deviations decrease reduction in between male female dies as are fixed, rise when settles. In addition, area, which close to...