Christina Nicolodi

ORCID: 0009-0000-5013-3782
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • Influenza Virus Research Studies
  • Immune Response and Inflammation
  • Respiratory viral infections research

2-deoxy-D-glucose is a synthetic glucose analog and potent inhibitor of glycolysis. Preclinical models demonstrated antiviral effects by inducing glucose-deprived state in cells, which interferes with viral replication. This was phase I, first-in-human, double-blind, randomized, placebo-controlled, dose-escalation trial single (cohort 1: 100µl one nostril, cohort 2: 200µl 3: both nostrils) multiple 4: four-times 200µl/day 5: nostrils, 6: six-times nostrils; all for seven days) ascending...

10.1016/j.ejps.2025.107069 article EN cc-by European Journal of Pharmaceutical Sciences 2025-03-01
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