A5009611003- Telomeres, Telomerase, and Senescence
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmacological Effects of Natural Compounds
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Proteins in Food Systems
- Galectins and Cancer Biology
- Cardiovascular Disease and Adiposity
- Management of metastatic bone disease
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Diagnosis and Treatment of Venous Diseases
- Traditional Chinese Medicine Analysis
- Multicomponent Synthesis of Heterocycles
- Liver Disease Diagnosis and Treatment
- Protein Hydrolysis and Bioactive Peptides
- Boron Compounds in Chemistry
- Crystallization and Solubility Studies
- Cardiovascular Health and Risk Factors
- Phytochemical compounds biological activities
- Cardiac Valve Diseases and Treatments
- Advanced Drug Delivery Systems
- Alcohol Consumption and Health Effects
- Medicinal Plants and Bioactive Compounds
- Lung Cancer Treatments and Mutations
- Cardiac and Coronary Surgery Techniques
Ruijin Hospital
2016-2024
Liaocheng People's Hospital
2020-2024
Shandong First Medical University
2023-2024
Shanghai Jiao Tong University
2024
Shandong University of Traditional Chinese Medicine
2024
Liaocheng University
2020-2023
Tianjin Economic-Technological Development Area
2021
Jilin Province Tumor Hospital
2021
Tianjin International Joint Academy of Biomedicine
2021
Zhengzhou Central Hospital
2020
Objective: To determine whether RAL affects perioperative outcomes and long-term efficacy in NSCLC patients, compared with traditional VAL. Summary of Background Data: is a promising treatment for NSCLC. However, its has not been fully evaluated. Methods: A single-center, open-labeled prospective randomized clinical trial was launched May 2017 to compare the By 2020, 320 patients were enrolled. The results VAL compared. Results: enrolled randomly assigned group (n = 157) 163). Perioperative...
Hyperglycemia-induced renal tubular cell injury is thought to play a critical role in the pathogenesis of diabetic nephropathy (DN). However, miRNAs remains be fully elucidated. The aim present study was investigate and mechanisms protecting against high glucose (HG)-induced apoptosis inflammation cells. First, we analyzed microRNA (miRNA) expression profiles kidney tissues from DN patients using miRNA microarray. It observed that miRNA-140-5p (miR-140-5p) significantly down-regulated with...
Quercetin is a flavonoid abundant in the plant kingdom. Various types of bioactivities quercetin have been demonstrated vitro. Although has proposed to exhibit numerous pharmacological benefits, it suffers from low bioavailability on account its obviously poor solubility water. Cocrystals generated interest recently as way enhancing dissolution vitro and creating relative insoluble medicine. In this study, quercetin-nicotinamide cocrystals were obtained via solvent evaporation technique....
In the present study, we identified 50 peptides that are classified into 21 peptide families with antioxidant and/or antimicrobial activity from Amolops daiyunensis, Pelophylax hubeiensis, Hylarana maosuoensis and Nanorana pleskei, which belong to four different genera in Ranidae Dicroglossidae families. These frog species were found for first time express (AOPs) (AMPs). include seven newly discovered daiyunin-1, daiyunin-2, daiyunin-3, maosonensis-1MS1, pleskein-1, pleskein-2, pleskein-3....
Background Poststroke depression and anxiety, independent predictor of poor functional outcomes, are common in the acute phase stroke. Up to now, there is no fast-onset antidepressive anxiolytic agents suitable for management ZL006-05, a dual-target analgesic we developed, dissociates nitric oxide synthase from postsynaptic density-95 while potentiates α2-containing γ-aminobutyric acid type A receptor. This study aims determine whether ZL006-05 can be used as an antistroke agent with...
SummaryBackgroundThe long-term survival and perioperative outcomes of robotic-assisted lobectomy (RAL) video-assisted (VAL) in resectable non-small-cell lung cancer (NSCLC) were found to be comparable retrospective studies, but they have not been investigated a randomized trial setting. We conducted the RVlob investigate if RAL was non-inferior VAL patients with NSCLC.MethodsIn this single-center, open-label, parallel-arm controlled Ruijin Hospital (Shanghai, China) between May 2017 2020, we...
Background We managed to assess and confirm the risk factors for mortality after coronary artery bypass grafting (CABG) operations so as map out proper guidance of surgical strategy especially in patients with low left ventricular ejection fraction (LVEF) domestic polyclinic like ours. Methods Five hundred forty-eight consecutive underwent CABG from December 1999 through August 2005 were analyzed retrospectively. Eighty-nine cases had an LVEF 40% or less. All together twenty-two candidate...
The study was to review the clinical manifestations and laboratory examinations of ectopic adrenocorticotropic hormone (ACTH) syndrome, analyze efficacy surgical treatment.The data, therapy, outcome 23 cases ACTH syndrome accompanied by intra-thoracic tumors were reviewed. removed from all patients according principles radical resection.The confirmed as associated with secretion in 19 cases. Hyperglycemia hypokalemia recovered, while plasma cortisol, 24-hour urinary free cortisol (UFC)...
Objective To compare the therapeutic effect, adverse reaction and effect on immunity of chemotherapy combined Aidi injection (AI) with those alone in treatment advanced non small cell lung cancer (NSCLC). Methods Ninety eight cases NSCLC were randomly divided into two groups, trial group control group. In group, NP plus AI (60 80 ml) given intravenously by dissolving 400 ml normal saline per day for 8-10 days, while only was given. Navelbine (25 mg/m 2, d1, 8) cisplastin (40 d1-3) chosen...
Eurycoma longifolia Jack is a plant of the genus in Simaroubaceae. Eurycomanone one mainquassinoids E. longifolia. Unfortunately, these quassinoids exhibit low bioavailability. In present study, phospholipid complex (TAF2-PC) was prepared to improve oral bioavailability TAF2 (Tongkat Ali Fraction 2). The complexation rate eurycomanone and used as index success complexes. effects reaction solvent, temperature, drug concentration, drug-lipid ratio time on were investigated. Response...
Aim: This study aimed to explore leukocyte telomere length (LTL) in the prediction of severity coronary artery disease (CAD). Materials & methods: A total 359 CAD patients who underwent angiography were enrolled this study. Severity was assessed by Gensini score (GS). Results: LTL is negatively correlated with GS (Spearman's rank correlation coefficient = -0.335; p < 0.001). Multivariate logistic regression results showed that an independent predictor high (p Area under curve value for...
Aim: This study aimed to explore the prognostic value of leukocyte telomere length (LTL) in patients with coronary artery disease (CAD). Materials & methods: We enrolled 366 CAD and 76 healthy subjects this study. LTL was measured. All were followed up for 6 months further analysis regarding major adverse cardiac events (MACEs). Results: had a significantly shortened compared (p < 0.05). The area under curve prediction MACEs 0.769 0.001), shorter being an independent predictor (Cox...