A5092937487- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Insect symbiosis and bacterial influences
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect and Arachnid Ecology and Behavior
- Virology and Viral Diseases
- CRISPR and Genetic Engineering
- Insect Pest Control Strategies
- CAR-T cell therapy research
- Virus-based gene therapy research
- COVID-19 epidemiological studies
The University of Texas Medical Branch at Galveston
2023-2025
University of California, Los Angeles
2022-2024
ABSTRACT Climate change is predicted to increase the spread of mosquito-borne viruses, but genetic mechanisms underlying influence environmental variation on ability insect vectors transmit human pathogens unknown. In response a changing climate, mosquitoes will experience longer periods drought. An important physiological dry environments protection against dehydration, here defined as desiccation tolerance. While temperature known impact interactions between mosquito and virus, role...
ABSTRACT As climate change alters Earth’s biomes, it is expected the transmission dynamics of mosquito-borne viruses will change. While effects temperature changes on mosquito-virus interactions and spread pathogens have been elucidated over last decade, impact relative humidity still relatively unknown. To overcome this knowledge gap, we exposed Aedes aegypti females to various conditions. We measured different components vectorial capacity such as survival, blood-feeding rates, in...
As climate change alters Earth's biomes, it is expected the transmission dynamics of mosquito-borne viruses will change. While effects temperature changes on mosquito-virus interactions and spread pathogens have been elucidated over last decade, relative humidity are still relatively unknown. To overcome this knowledge gap, we exposed
The composition of the microbiome is shaped by both environment and host in most organisms, but mosquito Aedes aegypti role shaping poorly understood. Previously, we had shown that four lines Ae. harbored different microbiomes when reared same insectary under identical conditions. To determine whether these differed from each other across time environments, characterized original at another institution. While it was clear influenced lines, did still observe distinct differences between...
Zika virus (ZIKV), a mosquito-borne human pathogen, causes dire congenital brain developmental abnormalities in children of infected mothers. The global health crisis precipitated by this has led to concerted effort develop effective therapies and prophylactic measures although, unfortunately, not very successfully. error-prone nature RNA viral genome replication tends promote evolution novel strains, which could cause epidemics pandemics. As such, our objective was safe...
In the face of climate change, mosquitoes will experience evolving climates including longer periods drought. An important physiological response to dry environments is protection against water loss or dehydration, here defined as desiccation tolerance. Various environmental factors temperature are known alter interactions between mosquito,