Mahana Sabachvili

ORCID: 0009-0000-9480-834X
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About
Contact & Profiles
Research Areas
  • Ion Channels and Receptors
  • Biochemical Analysis and Sensing Techniques
  • Olfactory and Sensory Function Studies

Saarland University
2025

Abstract Tracheal tuft cells shape immune responses in the airways. While some of these effects have been attributed to differential release either acetylcholine, leukotriene C4 and/or interleukin-25 depending on activating stimuli, cell-dependent mechanisms underlying recruitment and activation are incompletely understood. Here we show that Pseudomonas aeruginosa infection activates mouse cells, which ATP via pannexin 1 channels. Taste signaling through Trpm5 channel is essential for...

10.1038/s41467-025-55936-5 article EN cc-by Nature Communications 2025-01-10
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