Kumuthu S. Amaradasa

ORCID: 0009-0000-9562-8420
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About
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Research Areas
  • Receptor Mechanisms and Signaling
  • Synthesis of β-Lactam Compounds
  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Platelet Disorders and Treatments

University of Bristol
2023

Lung Institute
2023

Imperial College London
2023

Abstract Background and Purpose Ticagrelor is labelled as a reversible, direct‐acting platelet P2Y 12 receptor (P2Y R) antagonist that indicated clinically for the prevention of thrombotic events in patients with acute coronary syndrome (ACS). As many antiplatelet drugs, ticagrelor therapy increases bleeding risk patients, which may require transfusion emergency situations. The aim this study was to further examine reversibility at R. Experimental Approach Studies were performed human...

10.1111/bph.16204 article EN cc-by British Journal of Pharmacology 2023-08-02
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