- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- Hemoglobinopathies and Related Disorders
- Photoreceptor and optogenetics research
- GABA and Rice Research
- ATP Synthase and ATPases Research
- Advanced Fluorescence Microscopy Techniques
- Protein Structure and Dynamics
- Erythrocyte Function and Pathophysiology
- Iron Metabolism and Disorders
- Mitochondrial Function and Pathology
- Enzyme Structure and Function
- Heat shock proteins research
Moscow Institute of Physics and Technology
2023-2024
F-type ATP synthases play a key role in oxidative and photophosphorylation processes generating adenosine triphosphate (ATP) for most biochemical reactions living organisms. In contrast to the mitochondrial FOF1-ATP synthases, those of chloroplasts are known be mostly monomers with approx. 15% fraction oligomers interacting presumably non-specifically thylakoid membrane. To shed light on nature this difference we studied interactions chloroplast using small-angle X-ray scattering (SAXS)...
Branched-chain amino acids (BCAAs) play an important role in the functioning of mammalian cells and central nervous system. However, available genetically encoded indicators for BCAAs are based on Förster resonance energy transfer have a limited dynamic range. We developed single fluorescent protein-based sensor BCAAs, called NeIle, which is composed circularly permutated mNeonGreen protein inserted into leucine-isoleucine-valine binding (LIVBP) from