A5028568589- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Acute Ischemic Stroke Management
- Neuroscience and Neuropharmacology Research
- Drug Transport and Resistance Mechanisms
- Neurological Disorders and Treatments
- Neurological Disease Mechanisms and Treatments
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Cerebrovascular and genetic disorders
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Stroke Rehabilitation and Recovery
- Advanced Neuroimaging Techniques and Applications
- Inflammation biomarkers and pathways
- Cerebrovascular and Carotid Artery Diseases
- Substance Abuse Treatment and Outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroinflammation and Neurodegeneration Mechanisms
Wenzhou Medical University
2014-2025
Ruian People's Hospital
2016-2025
Neurology, Inc
2025
First Affiliated Hospital of Wenzhou Medical University
2014-2018
Recent studies have shown that cerebrospinal fluid (CSF) levels of soluble triggering receptor expressed on myeloid cells 1 (sTREM1) are elevated in individuals with Alzheimer's disease (AD), though the relationship between CSF sTREM1 and hippocampal atrophy remains to be elucidated. The primary aim this study was investigate association longitudinal changes volumes, determine if is moderated by cognitive status. We included 576 participants, comprising 152 cognitively unimpaired (CU) 424...
Objectives: Our purpose is to assess the role of total small vessel disease (SVD) burden affecting clinical outcome and develop validate a prognostic nomogram for minor ischemic stroke (MIS) patients. Methods: Between January 2018 April 2023, 454 MIS patients were enrolled. The functional was modified Rankin scale (mRS) score at 90 days. least absolute shrinkage selection operator (LASSO) regression multivariate logistic model used identify predictors, then drawn. Results: comprising...
Objective To evaluate and compare long-term effectiveness of five antiepileptic drugs (AEDs) for monotherapy adult patients with focal epilepsy in routine clinical practice. Methods Adult epilepsy, who were prescribed carbamazepine (CBZ), valproate (VPA), lamotrigine (LTG), topiramate (TPM), or oxcarbazepine (OXC) as monotherapy, during the period from January 2004 to June 2012 registered Wenzhou Epilepsy Follow Up Registry Database (WEFURD), included study. Prospective follow-up was...
Abstract Objective The models currently available for predicting the risk of seizure recurrence after antiepileptic drug (AED) withdrawal in adult epilepsy patients include prediction model developed by Lamberink et al (Lamberink model, 2017) and Medical Research Council (MRC 1993). However, there was no external validation two models. purpose this study to perform an independent a comparison MRC patients. Methods population recruited from Wenzhou Epilepsy Follow‐up Registry Database...
Ischemic stroke is the most common type of stroke. Intravenous thrombolytic therapy with alteplase currently effective method to improve prognosis patients acute cerebral infarction. The purpose this study was investigate efficacy and safety intravenous thrombolysis in ischemic combined atrial fibrillation analyze related influencing factors. It turns out, for ICS fibrillation, incidence sICH are lower than those without thrombolysis, but worse that fibrillation. At same time, baseline NHISS...
Background Cerebral small vessel disease (CSVD) is a significant contributor to both stroke and dementia. While numerous studies on CSVD have been published, herein, we conducted bibliometric examination of the literature CSVD, revealing its hot spots emerging patterns. Methods We used Web Science Core Collection as our primary database search from January 2008 2023. CiteSpace, VOSviewer, online platform, R-bibliometrix were employed conduct analysis network visualization, including number...
Background The Clot Burden Score (CBS) is used to assess thrombus length. influence of CBS on functional outcome was barely analyzed in patients with acute ischemic stroke (AIS) atrial fibrillation (AF). Purpose To the association between and clinical outcomes large vessel occlusion (LVO)-related AF who have undergone endovascular thrombectomy (EVT). Material Methods A total 160 were enrolled January 2021 April 2023. CTA-CBS score quantify burden. primary modified Rankin scale (mRS) at 90...