A5012319491- Catalytic Processes in Materials Science
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Phytochemical compounds biological activities
- Gas Sensing Nanomaterials and Sensors
- Advanced Photocatalysis Techniques
- Metal-Organic Frameworks: Synthesis and Applications
- Mosquito-borne diseases and control
- Spectroscopy and Laser Applications
- Computational Drug Discovery Methods
Universidad Autónoma Metropolitana
2022-2024
A series of six bis-furyl-pyrrolo[3,4-b]pyridin-5-ones synthesized via an Ugi-Zhu reaction coupled to a cascade process [aza Diels-Alder cycloaddition/N-acylation/aromatization] were evaluated in vitro against Dengue virus serotype 4 infection, and the replicon system encoding Renilla luciferase gen reporter. Also, silico studies on non-structural protein 3 (NS3), flavivirus protease comprising attractive target for development therapeutic antivirals bound 2B (NS3-NS2B) performed. The...
An Ugi-Zhu three-component reaction (UZ-3CR) coupled in one pot manner to a cascade process (
An Ugi-Zhu three-component reaction (UZ-3CR) coupled in a one-pot manner to cascade process (N-acylation/aza Diels-Alder cycloaddition/decarboxylation/dehydration) was performed synthesize series of pyrrolo[3,4-b]pyridin-5-ones 20% 92% overall yields using ytterbium triflate as catalyst, toluene solvent, and microwaves heat source. The synthesized molecules were evaluated vitro against breast cancer cell lines MDA-MB-231 MCF-7, finding that compound 1f, at concentration 6.25 μM, exhibited...
SBA-15 functionalized with APTES enables the selective detection of SO 2 molecule.
In this work, a bimetallic MOF UiO-66 Ce–Zr to degrade bisphenol A (BPA) in water was synthesised. The material exhibited remarkable degradation efficiency of 84.3% under UV irradiation for 240 minutes.