A5053774349- Multicomponent Synthesis of Heterocycles
- Synthesis of Tetrazole Derivatives
- Synthesis and biological activity
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Chemical Synthesis and Analysis
- Quinazolinone synthesis and applications
- Synthesis and Reactivity of Heterocycles
- Click Chemistry and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Radical Photochemical Reactions
- Synthesis and pharmacology of benzodiazepine derivatives
- Carbon Dioxide Capture Technologies
- Catalytic Processes in Materials Science
- Synthesis and Characterization of Pyrroles
- Synthetic Organic Chemistry Methods
- Synthesis and Biological Activity
- Phenothiazines and Benzothiazines Synthesis and Activities
- Covalent Organic Framework Applications
- Bioactive Compounds and Antitumor Agents
- Photochromic and Fluorescence Chemistry
- Inorganic Fluorides and Related Compounds
Universidad Autónoma Metropolitana
2016-2025
Ferro (United States)
2022-2024
Universidad de Guanajuato
2013-2017
Water and ethanol stabilities of the crystal structure Cu-based metal-organic framework (MOF) HKUST-1 have been investigated. Vapour (water ethanol) sorption isotherms cyclability were measured by a dynamic strategy. The capacity at 303 K remained unchanged contrasting water (which decreased along with experiment time). Considering binding energy each sorbate open Cu(ii) sites, obtained use diffusion coefficients, we showed superior stability towards ethanol. Finally, small quantity...
A broad variety of α-aminoamide-based compounds have been synthesized via the three-component version Ugi reaction (U-3CR) or by any its variants (Ugi-Zhu-3CR, Orru-3CR, Ugi-4C-3CR, Ugi-Joullié-3CR, GBB-3CR, Ugi-Reissert-3CR, and so on).
Almost two centuries have passed since Strecker synthesized for the first time α-aminoacid DL-alanine via a sequential combination of acetaldehyde with aqueous ammonia and hydrogen cyanide, coupled to further hydrolysis resulting α-aminonitrile using an acid solution. Since then, broad variety high valued products in various fields science technology been three-component reactions (3CRs) or one-pot methodologies involving 3CRs smartly processes like functionalizations, condensations, cross...
Heterogeneous catalysis, a cornerstone of the industry, offers practical advantage easy recovery and multiple reuses, leading to significant process cost reduction. The catalytic activity porous materials, such as silica-based, zeolites, MOFs, has proven be not just interesting, but also superior conventional heterogeneous systems. In this paper, we highlight importance these their advances modifications through years, use catalysts or support for other materials enhance properties. Resumen....
The dual-state emission (DSE) phenomenon has become crucial for developing luminogens (DSEgens) that exhibit efficient luminescence in both solution and solid states, addressing the limitations of conventional, phase-restricted...
A series of 18 3-tetrazolyl-tetrazolo[1,5-a]quinolines were synthesized in 21–90% yields via a novel one-pot Ugi-azide/SNAr/ring–chain azido-tautomerization process. We report also the synthesis 10 3-imidazo[1,2-a]pyridin-tetrazolo[1,5-a]quinolines 28–94% Groebke–Blackburn–Bienaymé/SNAr/ring–chain Both synthetic strategies involve use microwaves or ultrasound, and catalyst-free conditions. Finally, we show tetrazolo[1,5-a]quinoline-3-carbaldehyde tetrazolo[1,5-a]quinoline-3-dimethyl acetal...
A series of nine novel 3-tetrazolylmethyl-azepino[4,5-b]indol-4-ones were prepared in moderate to good overall yields only two reaction steps. The first step consisted a one-pot sequential process an Ugi-azide multicomponent reaction, N-acylation and SN2 give the xanthates. second was intramolecular cyclization under free radical conditions. Also, their binding modes have been modelled using docking techniques.
Crystalline Cu (<sc>ii</sc>)-MOP<bold>1</bold>was employed for the first time in catalytic conversion of<italic>trans</italic>-ferulic acid to vanillin.
A rapid and efficient synthesis of a series (±)-nuevamine, (±)-lennoxamine magallanesine aza analogues is described. The synthetic strategy involves Ugi-3CR two further condensation processes, aza-Diels-Alder cycloaddition the Pomeranz-Fritsch reaction. variation chain-size in aldehyde moieties provided structural diversity only operational reaction steps.
A series of novel 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1<i>H</i>-β-carbolines were prepared in good to excellent overall yields by an efficient MW-assisted one-pot Ugi-azide/Pictet–Spengler process. This work describes the first synthesis compounds including both 1,5-disubstituted 1<i>H</i>-tetrazole and 2,3,4,9-tetrahydro-1<i>H</i>-β-carboline heterocyclic systems.
In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), bacteria (Pseudomonas aeruginosa, Staphylococcus aureus), human fungal pathogens (Sporothrix schenckii, Candida albicans, tropicalis), which have become in a serious health problem, mainly tropical countries.
A series of six bis-furyl-pyrrolo[3,4-b]pyridin-5-ones synthesized via an Ugi-Zhu reaction coupled to a cascade process [aza Diels-Alder cycloaddition/N-acylation/aromatization] were evaluated in vitro against Dengue virus serotype 4 infection, and the replicon system encoding Renilla luciferase gen reporter. Also, silico studies on non-structural protein 3 (NS3), flavivirus protease comprising attractive target for development therapeutic antivirals bound 2B (NS3-NS2B) performed. The...
A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have wide range applications, such as chelating agents, organocatalysts and luminescent materials, mainly bioactive compounds.
Optically active bound-type bis-heterocycles were prepared by multicomponent reactions.
A series of fifteen 2-tetrazolylmethyl-isoindolin-1-one linked-type bis-heterocycles were synthesized in 10-76% yields under mild conditions via a one-pot Ugi-azide/(N-acylation/exo-Diels-Alder)/dehydration process from furan-2-ylmethanamine, aldehydes, isocyanides, azidotrimethylsilane, and maleic anhydride. Density functional theory calculations performed using the polarizable continuum model (toluene)-M06-2X-D3/6-311+G(d)//M06-2X-D3/6-31G(d) level to obtain full energy profile when...