A5102137896- Vitamin C and Antioxidants Research
- Reproductive tract infections research
- Rheumatoid Arthritis Research and Therapies
- Trace Elements in Health
- Pharmacological Effects of Natural Compounds
- Nanowire Synthesis and Applications
- Silicon Nanostructures and Photoluminescence
- Nanoplatforms for cancer theranostics
- Cytokine Signaling Pathways and Interactions
Seoul National University
2024
New Generation University College
2024
Seoul National University Hospital
2024
Glioblastoma (GBM) is one of the most common and fatal primary brain tumors, with a 5-year survival rate 7.2%. The standard treatment for GBM involves surgical resection followed by chemoradiotherapy, temozolomide (TMZ) currently only approved chemotherapeutic agent GBM. However, hydrolytic instability insufficient drug accumulation are major challenges that limit effectiveness TMZ chemotherapy. To overcome these limitations, we have developed delivery platform utilizing porous silicon...
Vitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties based on its antioxidative function. Aptamin C, complex of vitamin specific aptamer, has been reported to maintain or even enhance the efficacy while increasing stability. To investigate
Background/Objectives: Vitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties. However, its therapeutic applications are limited by rapid oxidation due to heat light sensitivity. Aptamin C, which employs aptamers bind vitamin has demonstrated enhanced stability efficacy. This study investigates the potential of inhibit progression pulmonary fibrosis, prominent inflammatory lung disease no effective treatment. Methods: Mice bearing bleomycin-induced...
Interleukin (IL)-32 is produced by T lymphocytes, natural killer cells, monocytes, and epithelial cells. IL-32 induces the production of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, IL-8, expression highly increased in rheumatoid arthritis (RA) patients. Enolase-1 (ENO1) a glycolytic enzyme stimulation ENO1 high levels concanavalin A (Con A)-activated peripheral blood mononuclear cells (PBMCs) macrophages RA In addition, there are many reports that anti-ENO1...
<title>Abstract</title> <bold>Background</bold> Trichomoniasis infected with <italic>Trichomonas vaginalis</italic> (<italic>T. vaginalis</italic>), can cause mild symptoms like itching and burning but also lead to more serious adverse outcomes. While typically treated metronidazole, this medication face resistance from <italic>T. some individuals may experience side effects. Hence, the research on effective therapeutic methods is essential improve traditional therapy for...