A5019951239- Clinical Laboratory Practices and Quality Control
- Digital Imaging for Blood Diseases
- Hemodynamic Monitoring and Therapy
- Dialysis and Renal Disease Management
- Rabbits: Nutrition, Reproduction, Health
- Inflammatory Biomarkers in Disease Prognosis
- Blood properties and coagulation
- Therapeutic Uses of Natural Elements
- Hemophilia Treatment and Research
- Statistical Methods in Clinical Trials
- Erythrocyte Function and Pathophysiology
- Blood groups and transfusion
- Cell Image Analysis Techniques
- Meta-analysis and systematic reviews
- Renal function and acid-base balance
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Reliability and Agreement in Measurement
- Liver Disease and Transplantation
- Health, Medicine and Society
- Venous Thromboembolism Diagnosis and Management
University of Parma
2012-2024
Ospedale di Parma
2014
Background: Extended half-life (EHL) factor IX (FIX) concentrates allow for prophylaxis with prolonged dosing intervals and high bleeding protection in persons hemophilia B. Long-term real-world studies are lacking. Methods: In a retrospective-prospective study, the six-year use of EHL recombinant FIX-albumin fusion protein (rIX-FP) was analyzed, comparing outcomes previous standard (SHL) FIX patients already on prophylaxis. Results: Prophylaxis rIX-FP prescribed 15 (10 severe, 5 moderate;...
Abstract Introduction Recent automated hematology analyzers ( HA s) can identify and report nucleated red blood cells NRBC ) count as a separate population out of white WBC ). The aim this study was to investigate the analytical performances enumeration on five top range s. Methods We evaluated within‐run between‐day precision, limit blank (LoB), detection (LoD), quantitation (LoQ) XE ‐2100 XN ‐module (Sysmex), ADVIA 2120i (Siemens), BC ‐6800 (Mindray), UniCel DxH 800 (Beckman Coulter)....
Although microscopy still represents the gold standard for cytometric analysis of peritoneal fluids, automated flow cytometry may improve throughput and accuracy. We evaluated performance total nucleated cell (TNC), white blood (WBC), polymorphonuclear (PMN), mononuclear (MONO) counts Sysmex XE-5000 on fluids. The imprecision was excellent, being always lower than 11%, whereas linearity studies yielded correlation coefficients 1.00 all parameters. carryover 0.2%. comparison between...
Abstract Background The aims of this study were to compare the diagnostic accuracy blood smear review criteria, by means three different panel rules, those proposed by: International Consensus Group for Hematology [41‐ ICGH rules], Italian Survey [ IS rules] and Working on Hematology‐ SIB ioC ( WGH ) consensus rules rules). Methods This is based 2707 peripheral PB samples referred routine hematological testing ‐associated laboratories displaced all over territory. processed seven hematology...
Abstract Introduction The correctness of the results automated platelet analysis is still highly debated. aim this multicenter study, conducted according to international guidelines, was verify analytical performance nine different types hematology analyzers (HAs) in analysis. Methods Four hundred eighty‐six peripheral blood samples (PB), collected K 3 EDTA tubes, were analyzed by ABX Pentra, ADVIA2120i, BC‐6800, BC‐6800 Plus, Cell‐DYN Sapphire, DxH800, XE‐2100, XE‐5000, XN‐20 with PLT‐F...
We planned an original study to investigate the morphological changes caused by spurious hemolysis of whole-blood samples, analyzed using automated image analysis system. Seven specimens anticoagulated with EDTA were pooled and divided in two aliquots. The former was left untreated, whereas latter subjected mechanical forced aspiration insulin syringe. complete blood cell count performed on a Sysmex XE-2100, aliquots then processed CellaVision DM96. In spuriously hemolyzed main findings...
Aims Optical microscopic (OM) evaluation of peripheral blood (PB) cells is still a crucial step the laboratory haematological workflow. The morphological cell analysis time-consuming and expensive it requires skilled operator. To address these challenges, automated image-processing systems, as digital morphology (DM), were developed in last few years. aim this multicentre study, performed according to international guidelines, verify analytical performance DM compared with manual OM,...
La presenza di eritroblasti (nucleated red blood cells, NRBC) nel sangue periferico (SP) soggetti talassemici con drepanocitosi e nei neonati è indice alterata attività eritropoietica: primi correla il fabbisogno trasfusionale secondi l’indice mortalità le complicanze perinatali. Questo studio valuta performance ADVIA2120i (Siemens) per conteggio degli NRBC tre gruppi sopra menzionati, accomunati da una potenziale sensibilità delle emazie ai sistemi strumentali lisi dalla necessità un...