Nikil Badey

ORCID: 0009-0001-3917-0520
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About
Contact & Profiles
Research Areas
  • Hidradenitis Suppurativa and Treatments
  • Acne and Rosacea Treatments and Effects
  • Plant tissue culture and regeneration
  • Trace Elements in Health
  • Magnetic Bearings and Levitation Dynamics
  • Oral Health Pathology and Treatment
  • Protein Degradation and Inhibitors
  • Ubiquitin and proteasome pathways
  • Chromosomal and Genetic Variations
  • CRISPR and Genetic Engineering
  • Cancer-related Molecular Pathways

Harvard University
2023-2024

University of Minnesota
2020-2022

Joint Center for Structural Genomics
2020

Abstract Acne vulgaris, rosacea, and hidradenitis suppurativa are enduring inflammatory skin conditions that frequently manifest with akin clinical attributes, posing a considerable challenge for their distinctive diagnosis. While these do exhibit certain resemblances, they also demonstrate distinct underlying pathophysiological mechanisms treatment modalities. Delving into both the molecular parallels disparities among three disorders can yield invaluable insights refined diagnostics,...

10.1111/exd.15145 article EN Experimental Dermatology 2024-07-01

Abstract TP53 functions as a central regulator in response to DNA damage and other cell stressors by inducing the expression of many protective pathways such cycle arrest apoptosis. Consequently, this gene is often found disrupted human cancers. Elephants are particularly interesting species for study cancer, virtue their large number divisions long lives yet low incidence cancer. also possess multiple retrogene copies TP53, which have previously been shown induce strong cellular responses...

10.1101/2024.09.07.611789 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-07

ABSTRACT Acne vulgaris, rosacea, and hidradenitis suppurativa are enduring inflammatory skin conditions that frequently manifest with akin clinical attributes, posing a considerable challenge for their distinctive diagnosis. While these do exhibit certain resemblances, they also demonstrate distinct underlying pathophysiological mechanisms treatment modalities. Delving into both the molecular parallels disparities among three disorders can yield invaluable insights refined diagnostics,...

10.1101/2023.11.28.23299152 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-11-29

Abstract Tissue culture methods which serve as the standard to regenerate modified plants are challenging and have limited capacity engineer new accessions. To improve upon these techniques, genome modifying reagents been combined with developmental regulators create gene edited plant tissues in both monocot eudicot species. Co-culturing seedlings Agrobacterium strains encoding regulatory genes has proved be effective at producing de novo meristems multiple In order see that this technology...

10.1101/2022.11.15.516675 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-11-17
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