Michelle Cai

ORCID: 0009-0001-4319-4509
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About
Contact & Profiles
Research Areas
  • Acute Myeloid Leukemia Research
  • Epigenetics and DNA Methylation
  • Histone Deacetylase Inhibitors Research
  • Protein Degradation and Inhibitors
  • Cancer-related gene regulation
  • Ion Channels and Receptors
  • Antioxidant Activity and Oxidative Stress
  • Autophagy in Disease and Therapy
  • Cancer Genomics and Diagnostics
  • Advanced biosensing and bioanalysis techniques
  • Extracellular vesicles in disease
  • Photoacoustic and Ultrasonic Imaging

Washington University in St. Louis
2023-2024

Western University
2017-2018

Transnational Press London
2017

Atherosclerosis is characterized by the accumulation of lipids within arterial wall. Although activation TRPV1 cation channels capsaicin may reduce lipid storage and formation atherosclerotic lesions, a clinical use for has been limited its chronic toxicity. Here we show that coupling copper sulfide (CuS) nanoparticles to antibodies targeting act as photothermal switch signaling in vascular smooth muscle cells (VSMCs) using near-infrared light. Upon irradiation, local increases temperature...

10.1038/s41467-017-02657-z article EN cc-by Nature Communications 2018-01-09

A H<sub>2</sub>O<sub>2</sub>-responsive and plaque-penetrating S2P–CeO<sub>2</sub>–ASOs nanoplatform was developed for the effective silencing of mTOR treatment atherosclerosis.

10.1039/c7sc03582a article EN cc-by Chemical Science 2017-10-27

Here, we characterize the DNA methylation phenotypes of bone marrow cells from mice with hematopoietic deficiency

10.1126/sciadv.adk8598 article EN cc-by-nc Science Advances 2024-01-31
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