A5100462463- Supramolecular Self-Assembly in Materials
- Molecular Sensors and Ion Detection
- Supramolecular Chemistry and Complexes
- Organoselenium and organotellurium chemistry
- Luminescence and Fluorescent Materials
- Hydrogen Storage and Materials
- Advanced Nanomaterials in Catalysis
- Advanced Photocatalysis Techniques
- Advancements in Battery Materials
- Mycobacterium research and diagnosis
- Selenium in Biological Systems
- Graphene research and applications
- Advanced battery technologies research
- Pneumonia and Respiratory Infections
- Photochromic and Fluorescence Chemistry
- Porphyrin and Phthalocyanine Chemistry
- Quantum Dots Synthesis And Properties
- Organic Electronics and Photovoltaics
- Covalent Organic Framework Applications
- Boron and Carbon Nanomaterials Research
- Biofuel production and bioconversion
- Polydiacetylene-based materials and applications
- Sepsis Diagnosis and Treatment
- Magnetism in coordination complexes
- Fungal Infections and Studies
Northwestern Polytechnical University
2017-2025
University of Florida
2016-2025
Huashan Hospital
2022-2024
Fudan University
2022-2024
Changzhou University
2022-2024
Central South University
2022-2023
Jiangsu University of Science and Technology
2019-2023
Nanjing University of Posts and Telecommunications
2022-2023
Hangzhou Hospital of Traditional Chinese Medicine
2023
Xiangya Hospital Central South University
2023
In cooperative catalysis, the combination of chemo- and biocatalysts to perform one-pot reactions is a powerful tool for improvement chemical synthesis. Herein, UiO-66-NH2 was employed stepwise immobilize Pd nanoparticles (NPs) Candida antarctica lipase B (CalB) fabrication biohybrid catalysts cascade reactions. Distinct from traditional materials, has robust but tunable structure that can be utilized with ligand exchange approach adjust its hydrophobicity, resulting in excellent catalyst...
Proteins are co-translationally inserted into the bacterial plasma membrane via SecYEG translocon by lateral release of hydrophobic transmembrane segments phospholipid bilayer. The trigger for opening is not known. Here we monitor photo-induced electron transfer (PET) between two fluorophores attached to SecY helices at rim gate. In resting translocon, fluorescence quenched, consistent with a closed conformation. Ribosome binding diminishes PET quenching, indicating effect larger ribosomes...
Sunlight-driven hydrogen production provides a sustainable solution for clean energy generation. Despite their potential, extracellular photosensitized biohybrid systems are typically hindered by sluggish electron transfer between semiconductor materials and microorganisms. Herein, we introduce bioinspired development, the membrane-anchoring protein approach, to overcome this limitation. Using incorporated with TiO2 binding peptide on engineered E. coli, establish proof-of-concept...
Abstract The explosive growth of information and its widespread availability underscores the need for robust encryption anticounterfeiting measures. In this study, CdS quantum dots are engineered (QDs) to manifest multiple visual responses a single trigger through strategic ligand design. surface engineering method allows QDs transition from yellow black upon photoexcitation‐induced electron transfer Cd(II) Cd(0). Surface ligands desorption under hole injection, leading an increase in size...
Genome-wide association studies have identified SH2B3 as an important non-MHC gene for islet autoimmunity and type 1 diabetes (T1D). In this study, we found a single haplotype significantly associated with increased risk human T1D. Fine mapping has demonstrated the most credible causative variant is nucleotide rs3184504*T polymorphism in SH2B3. To better characterize role of T1D, used mouse modeling T cellintrinsic regulating peripheral tolerance. deficiency had minimal effect on TCR...
Allosteric modulation of protein function, which involves effector binding triggering distant conformational changes, is crucial for cellular and metabolic control. However, achieving tunable control, structural diversity, precise intracellular regulation remains challenging. Here, we designed dynamic supramolecular assemblies driven by enzyme-substrate interactions antioxidant in cells. Using a glutathione S-transferase modified with cysteine mutation (GSTK77C), engineered an molecule...
The recent studies show that Large Language Models (LLMs) often fall short in tasks demanding creative, lateral thinking due to lacking a clear awareness of their own reasoning processes. To cope with this issue, we propose novel metacognitive prompting method (titled as MP) by mimicking human metacognition. Through integrating principles, MP endows LLMs ability, thereby enhancing abilities strategize, monitor, and reflect on responses when dealing creative tasks. experimental results five...
Abstract Background Xylanase is one of the most extensively used biocatalysts for biomass degradation. However, its low catalytic efficiency and poor thermostability limit applications. Therefore, improving properties xylanases to enable synergistic degradation lignocellulosic with cellulase considerable significance in field bioenergy. Results Using fragment replacement, we improved performance a GH10 xylanase, XylE. Of ten hybrid enzymes obtained, seven showed xylanase activity....
A facile strategy of the assembly CQD/Bi<sub>2</sub>WO<sub>6</sub> hybrid materials, which exhibit highly efficient photocatalytic degradation pollutants under visible light.
Perampanel (PER) has previously been shown to be effective and tolerable when used as an adjunctive therapy for patients with focal-onset seizures (FOS). This study aimed evaluate the effect of PER FOS in Chinese population under real-world conditions 1 year.A prospective, single-center, 1-year observational was conducted at Huashan Hospital, enrolling both age (≥4 years old) adult FOS. Response assessed 3-, 6-, 12-month checkpoints by analyzing 50 % responder rate, seizure-free reduction...
The self-assembled and highly ordered first layer of terephthalic acid on Cu(100) as well its bilayer the same surface are studied here using high-resolution electron energy loss spectroscopy (HREELS), Auger spectroscopy, low diffraction. These experiments show completion before growth second layer. HREELS measurements that deprotonates, which is seen in absence OH stretching mode for groups. However, this present structure, confirming deprotonation due to a reaction with Cu suggesting there...
Abstract The chemistry of aqueous salt solutions is rich with ambiguities, especially in stimuli‐responsive supramolecular systems. Rational use ion specificity to design responsive materials, however, remains a challenging task. In this work, low‐molecular‐weight system was developed that used reveal the underlying systematic relationship between ions, water, and solutes. By utilizing these water‐attenuated forces (with K only ca. 30 m −1 ), an alternative concept for fabricating ionic...
A crown ether-functionalized poly(vinyl alcohol) (PVA) system shows lower critical solution temperature (LCST) phase separation behavior in water.
Abstract The exploration of effective platforms for immobilizing chemo‐ and biocatalysts to develop biohybrid catalysts is an attractive subject practical interest. In this work, carbon nitride (C 3 N 4 ) used the first time as a platform immobilization metal catalyst (Pd nanoparticles) biocatalyst ( Candida antarctica lipase B, CalB) in facile manner prepare catalyst. optimal inherits intrinsic performance both Pd nanoparticles CalB, shows high activity one‐pot cascade reaction converting...
Potassium deposition in ultrahigh vacuum on a self-assembled monolayer (SAM) of 1-dodecanethiol Au(111) results penetration large fraction the metal to gold−SAM interface, as determined by angle-resolved X-ray photoelectron spectroscopy (XPS) and high-resolution XPS. This change work function (WF) surface, due WF gold substrate beneath SAM. The measured binding energy C1s photoemission peak related aliphatic chain also shifts correlates directly with WF. In contrast, S2p from thiolate...
For designing water-soluble responsive materials, utilizing crown ethers as main building blocks has been rarely explored in contrast to their linear poly(ethylene glycol) counterparts. In the current study, we report robust thermoresponsive properties of benzo-21-crown-7 (B21C7) family with lower critical solution temperature (LCST) and upper (UCST) behavior. Different substituent groups on benzene ring exhibit significant effects water solubility thermoresponsiveness. B21C7 its cyano...