A5083899753- Genomics and Rare Diseases
- Neurogenetic and Muscular Disorders Research
- Prenatal Screening and Diagnostics
- Genetic and phenotypic traits in livestock
- Congenital gastrointestinal and neural anomalies
- Genomic variations and chromosomal abnormalities
- Digestive system and related health
- Congenital Anomalies and Fetal Surgery
- Parvovirus B19 Infection Studies
- Genetic Associations and Epidemiology
- Inflammasome and immune disorders
- Forensic Anthropology and Bioarchaeology Studies
- Metabolism and Genetic Disorders
- Pleistocene-Era Hominins and Archaeology
- Nutrition, Genetics, and Disease
- Archaeology and ancient environmental studies
- Forensic and Genetic Research
- Congenital heart defects research
University of Liège
2024-2025
Center of Medical Genetics and Primary Health Care
2011-2022
Centre Hospitalier Universitaire Sainte-Justine
2007-2011
Université de Montréal
2007-2011
Recent work on the Neandertal genome has raised possibility of admixture between Neandertals and expanding population Homo sapiens who left Africa 80 50 Kya (thousand years ago) to colonize rest world. Here, we provide evidence a notable presence (9% overall) Neandertal-derived X chromosome segment among all contemporary human populations outside Africa. Our analysis 6,092 X-chromosomes from inhabited continents supports earlier contentions that mosaic lineages different time depths...
Genomic newborn screening programs are emerging worldwide. With the support of local pediatric team Liege, Belgium, we developed a panel 405 genes that associated with 165 early-onset, treatable diseases goal creating test using targeted next-generation sequencing for all treatable, and serious conditions.
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest in adulthood. It has been suggested that the historical introduction dairying led positive selection for persistence variants regulatory region upstream LCT gene. Here, we genotyped 202 Armenian subjects LCT-13910T, variant which widespread Europeans. The homozygous C/C genotype associated with primary hypolactasia, heterozygous C/T T/T genotypes were found 191...