Yuhang Chen

ORCID: 0009-0001-5326-008X
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About
Contact & Profiles
Research Areas
  • Platelet Disorders and Treatments
  • Biochemical and Structural Characterization
  • Enzyme Structure and Function
  • Epigenetics and DNA Methylation
  • Insect and Pesticide Research
  • Hereditary Neurological Disorders
  • Glycogen Storage Diseases and Myoclonus
  • Signaling Pathways in Disease
  • Hemostasis and retained surgical items
  • Advanced Graph Neural Networks
  • Recommender Systems and Techniques
  • Peptidase Inhibition and Analysis
  • Polyamine Metabolism and Applications
  • Neurological disorders and treatments
  • Electrospun Nanofibers in Biomedical Applications

Zhejiang Normal University
2023

Nanfang Hospital
2021

Southern Medical University
2021

Tsinghua University
2001-2002

Staphylokinase (SAK) is a 15.5‐kDa protein from Staphylococcus aureus that activates plasminogen by forming 1 : complex with plasmin. Recombinant SAK has been shown in clinical trials to induce fibrin‐specific clot lysis patients acute myocardial infarction. However, elicits high titers of neutralizing antibodies. Biochemical and engineering studies have demonstrated the feasibility generating variants reduced antigenicity yet intact thrombolytic potency. Here, we present X‐ray...

10.1046/j.0014-2956.2001.02706.x article EN European Journal of Biochemistry 2002-01-01

Graph contrastive learning (GCL) has recently attracted great attention as a popular approach to reduce the label reliance in graph representation learning. However, current GCL models still encounter some issues, such collapse. In order tackle this issue, we propose an innovative self-supervised method, named CRGCL. Specifically, first employ random augmentation create two views of input graph, then adopt redundancy reduction principle enhance consistency between views. Besides, add...

10.1145/3650400.3650465 article EN Proceedings of the 2021 5th International Conference on Electronic Information Technology and Computer Engineering 2023-10-20
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