A5042822991- Legionella and Acanthamoeba research
- Bacterial Infections and Vaccines
- Amoebic Infections and Treatments
- Immune Response and Inflammation
- Extracellular vesicles in disease
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immunotherapy and Immune Responses
Autonomous University of Tlaxcala
2024-2025
Universidad Nacional Autónoma de México
2024-2025
Instituto Politécnico Nacional
2018-2022
Abstract Naegleria fowleri is an amoeba that causes a fatal disease in the central nervous system known as primary amoebic meningoencephalitis (PAM) humans. Most of infections are acquired by people who practice recreational activities water contaminated with trophozoites. Swimming and wading irrigation channels Mexicali common practices for local people. Although there some warning signposts surrounding sites, continue using these purposes. In region, cases PAM have been reported; however,...
Naegleria fowleri is a free-living amoeba, which able to infect humans through the nasal mucosa causing disease in central nervous system known as primary amoebic meningoencephalitis (PAM). Polymorphonuclear cells (PMNs) play critical role early phase of N infection. Recently, new biological defence mechanism called neutrophil extracellular traps (NETs) has been attracting attention. These structures represent an important strategy immobilize and kill invading microorganisms. In this work,...
The aims of this work were to evaluate the protective role 250-kDa polypeptide band Naegleria fowleri. We designed an immunization strategy in Balb/c mice which inoculated by i.n. route with electrocuted N. observed that induced 80% protection, whereas coadministration Cholera Toxin 100% protection. Moreover, high levels IgA- and IgG-specific antibodies detected ELISA assay. also analysed migration molecules (α4β1 LFA-1) on T B lymphocytes nose-associated lymphoid tissue (NALT), cervical...