A5103267518- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Cancer-related molecular mechanisms research
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Pediatric Hepatobiliary Diseases and Treatments
- Appendicitis Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Diabetes and associated disorders
Zhejiang Chinese Medical University
2022-2024
Zhejiang University
2022
Hangzhou First People's Hospital
2022
Background Cuproptosis is a novel type of mediated cell death strongly associated with the progression several cancers and has been implicated as potential therapeutic target. However, role cuproptosis in cholangiocarcinoma for prognostic prediction, subgroup classification, strategies remains largely unknown. Methods A systematic analysis was conducted among 146 cuproptosis-related genes clinical information based on independent mRNA protein datasets to elucidate mechanisms prediction value...
Introduction Acute pancreatitis (AP) is an inflammatory disease with very poor outcomes. However, the order of induction and coordinated interactions systemic response syndrome (SIRS) compensatory anti-inflammatory (CARS) potential mechanisms in AP are still unclear. Methods An integrative analysis was performed based on transcripts blood from patients different severity levels (GSE194331), as well impaired lung (GSE151572), liver (GSE151927) pancreas (GSE65146) samples experimental model to...
Abstract Background Cuproptosis is a novel type of mediated cell death strongly associated with the progression several cancers and has been implicated as potential therapeutic target. However, role cuproptosis in cholangiocarcinoma (CCA) for prognostic prediction, subgroup classification, strategies remains largely unknown. Methods A systematic analysis was conducted among 146 cuproptosis-related genes (CRGs) clinical information based on independent mRNA protein datasets to elucidate...
Abstract Background: Cholangiocarcinoma (CCA) is a rare malignant carcinoma characterized by high mortality, challenging diagnosis, and poor prognosis. A powerful prediction biomarker urgently needed for the early diagnosis individualized treatment of CCA patients. Methods: systematic bioinformatics analysis was conducted based on mRNA expression data clinical information from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) National Genomics Data Center (NGDC) datasets....