- Family Support in Illness
- Tryptophan and brain disorders
- Treatment of Major Depression
- Mindfulness and Compassion Interventions
- Cancer survivorship and care
- Mental Health Research Topics
- Childhood Cancer Survivors' Quality of Life
University of Exeter
2024
Harvard University
2008
Dana-Farber Cancer Institute
2006
Massachusetts General Hospital
2006
The objectives of this study were to describe the quality life (QOL), consequences treatment, complementary therapy use, and factors correlating with psychologic state in 58 survivors early-stage ovarian cancer since little is known about QOL survivors. Survivors interviewed using standardized measures assess physical, psychologic, social, sexual functioning; impact on socioeconomic status; use. reported good physical scores few unmet needs. However, menopausal symptoms negative sexuality...
Alcohol use disorder (AUD) is a major public health issue, posing harmful consequences for individuals and society. Recent advances in addiction research have highlighted the therapeutic potential of ketamine-assisted therapy AUD. However, exact mechanisms underlying its effectiveness remain unknown.
Ketamine, often associated with its frequent illicit recreational use, is renowned as an approved alternative for treatment-resistant depression. This paper evaluates the mechanism of ketamine's role in treating depression, emphasising positive safety profile and acute onset action. Ketamine's action involves antagonism N-methyl-D-Aspartate (NMDA) receptors, leading to increased glutamate production brain regions mood regulation. Moreover, ketamine counteracts effects chronic stress by...
5024 Background: Quality of life (QOL) assessments in early stage (stage I and II) ovarian cancer survivors (CS) are limited have to date not focused on CS who received adjuvant platinum- taxane-based chemotherapy (CT). Methods: 55 patients (pts) were identified from patient logs the Dana-Farber Cancer Institute Massachusetts General Hospital. 54 pts. CT. QOL long-term medical sequelae measured pts > 3 years diagnosis had no evidence recurrent cancer. Pts interviewed by phone, following...