A5041229001- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Muscle and Compartmental Disorders
- MicroRNA in disease regulation
- Connective Tissue Growth Factor Research
- Occupational Health and Performance
- Liver Disease Diagnosis and Treatment
- Cell death mechanisms and regulation
- Lung Cancer Treatments and Mutations
- SARS-CoV-2 and COVID-19 Research
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Multilevel Inverters and Converters
- Pulmonary Hypertension Research and Treatments
- Bioinformatics and Genomic Networks
- Heat shock proteins research
- Musculoskeletal pain and rehabilitation
- Endoplasmic Reticulum Stress and Disease
- Advanced DC-DC Converters
- Electromagnetic Compatibility and Noise Suppression
- Ubiquitin and proteasome pathways
Fudan University
2020
Kunming Medical University
2013-2020
First Affiliated Hospital of Kunming Medical University
2020
Xuzhou Medical College
2018
Rhabdomyolysis (RM) has been associated with many viral infectious diseases, and poor outcomes. We aim to evaluate the clinical features outcomes of RM in patients coronavirus disease 2019 (COVID-19).This was a single-center, retrospective, cohort study 1,014 consecutive hospitalized confirmed COVID-19 at Huoshenshan Hospital Wuhan, China, between February 17 April 12, 2020.The overall incidence 2.2%. Compared without RM, those tended have higher risk deterioration. Patients also constituted...
Nonalcoholic fatty liver disease (NAFLD) is a global health problem characterized by excessive accumulation of fat in the without effect other pathological factors including hepatitis infection and alcohol abuse. Current studies indicate that gene play important roles development NAFLD. However, molecular characteristics differentially expressed genes (DEGs) associated mechanisms with NAFLD have not been well elucidated. Using two microarray data expression profiling tissues mice models, we...
Purpose Caspase 8 (CASP8) plays a critical role in the apoptotic pathway and aberrant regulation of this causes many diseases including cancers. Genetic variants rs3834129 (CTTACT/−) rs3769821 (T/C) promoter region CASP8 gene were documented to be associated with multiple solid cancers non-Hodgkin’s lymphoma (NHL), respectively, despite some controversies. We aimed discern potential association these two rs113686495 (CTGTCATT/−), as well mRNA protein expression levels colorectal cancer (CRC)...
Abstract Purpose: To evaluate the clinical features and outcomes of rhabdomyolysis (RM) in patients with COVID-19. Method: A single center retrospective cohort study 1,014 consecutive hospitalized confirmed COVID-19 at Huoshenshan hospital Wuhan, China, between February 17 April 12, 2020. Results: The overall incidence RM was 2.2%. Comparing without RM, tended to have a higher risk deterioration, representing by ratio be admitted intensive care unit (ICU) (90.9 % vs 5.3%, P <0.001),...
miR-382-3p can regulate apoptosis through multiple pathways, but the mechanism remains unknown. In this experiment, we explored whether modulate N-methyL-D-aspartate (NMDA)- induced HT22 cell by regulating RhoC/ROCK1 signaling pathway. An excitatory neurotoxicity model of cells was in vitro with 2 mmol/L NMDA. The were divided into normal control, NMDA-induced, NMDA + mimic, and inhibitor groups. 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) method, Real-time PCR,...
This paper presents Buck-Boost converter with four operation modes which can be used in automotive systems. The proposed employs fixed frequency peak current mode control, an adaptive offset cancellation (AOC) technique reduces output overshoot/undershoot voltages and settling time during transitions. is designed 0.18μm BCD process. operates a wide input voltage range from 5 to 60V, 12V voltage, maximum load of 6A switching 700KHz. simulation results under different conditions show that...
Abstract Background: Coronavirus disease 2019 (COVID-19) has outbroken in Wuhan, China, December, 2019, and became a global pandemic.No effective antiviral agents were approved for COVID-19. In this study, we aim to evaluate the efficacy outcomes of Lianhuaqingwen (LH) capsulein patients with Methods: retrospective cohort included 147 hospitalized laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)infection between February 4 th April 15 , 2020, Wuhan Huoshen...