A5026734494- Malaria Research and Control
- Mosquito-borne diseases and control
- HIV/AIDS Research and Interventions
- Drug-Induced Hepatotoxicity and Protection
- HIV/AIDS drug development and treatment
- HIV/AIDS Impact and Responses
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- HIV Research and Treatment
- Blood groups and transfusion
- Blood Pressure and Hypertension Studies
- Neurological Complications and Syndromes
- Hormonal Regulation and Hypertension
- Adolescent Sexual and Reproductive Health
- Vibrio bacteria research studies
- Pharmacological Effects of Natural Compounds
- HIV-related health complications and treatments
- Diet and metabolism studies
- Hemoglobinopathies and Related Disorders
UNSW Sydney
2024
East Yangon General Hospital
2016-2023
Myanmar Oxford Clinical Research Unit
2020
In this randomized controlled study, individuals taking dolutegravir+darunavir/ritonavir had greater increases in systolic and diastolic blood pressure than those 2 nucleoside reverse-transcriptase inhibitors+darunavir/ritonavir at week-48. The difference remained significant after controlling for confounding factors, including weight gain.
Background. African children with severe falciparum malaria commonly have concomitant Gram-negative bacteremia, but co-infection has been thought to be relatively rare in adult malaria. Methods. Adults a diagnosis of hospitalized at 4 tertiary referral hospitals Myanmar had blood cultures collected admission. The frequency bacteremia and the clinical characteristics patients, without were explored. Results. Of 67 adults malaria, 9 (13% [95% confidence interval, 5.3%-21.6%]) also bacteremic...
It has been believed that concomitant bacteremia is uncommon in adults hospitalized with falciparum malaria. Accordingly, the World Health Organization treatment guidelines presently only recommended additional antibacterial therapy these patients if they have a clinical syndrome compatible serious bacterial infection. Admission blood cultures were collected from 20 consecutive Myanmar, positive immunochromatographic test and film, suggesting diagnosis of malaria; four (20%) had clinically...
To evaluate a decentralised testing model and simplified treatment protocol of hepatitis C virus (HCV) infection to facilitate scale-up in Myanmar, this prospective, observational study recruited HIV–HCV co-infected outpatients receiving sofosbuvir/daclatasvir Yangon, Myanmar. The examined the outcomes factors associated with sustained virological response (SVR). A “hub-and-spoke” was evaluated where fingerstick capillary specimens were transported by taxi processed centrally. performance...
There is a growing recognition of the impact gender and social determinants health on clinical course people living with HIV (PLHIV). However, relative contribution these factors to outcomes PLHIV incompletely defined in many countries. This study was performed gain greater understanding non-clinical prognosis Myanmar.
Journal Article Accepted manuscript Refining our understanding of the association between integrase inhibitor therapy and elevations in blood pressure Get access Phyo Pyae Nyein, Nyein The Kirby Institute, University New South Wales, Sydney, Australia Corresponding author: Email: p.nyein@unsw.edu.au, Address: south Wallace Wurth Building (C27), Corner High Street & Botany Street, UNSW, Kensington NSW 2052, Search for other works by this author on: Oxford Academic PubMed Google Scholar Kathy...
Background: Simplification and decentralisation of the treatment hepatitis C virus (HCV) infection is crucial for scale-up in low- middle-income countries (LMIC).Methods: This prospective, observational study recruited human immunodeficiency (HIV)-HCV co-infected outpatients receiving sofosbuvir/daclatasvir at hospitals Yangon, Myanmar. The examined outcomes using a simplified model care factors associated with sustained virological remission (SVR). evaluated utility decentralised...