A5102880580- Metastasis and carcinoma case studies
- Cancer-related molecular mechanisms research
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Autophagy in Disease and Therapy
- Advanced Breast Cancer Therapies
- Bone Tumor Diagnosis and Treatments
- RNA modifications and cancer
- MicroRNA in disease regulation
- DNA Repair Mechanisms
- Cancer Immunotherapy and Biomarkers
- Fungal Infections and Studies
- Head and Neck Cancer Studies
- Cancer-related Molecular Pathways
- Plant Pathogens and Fungal Diseases
- Oral and Maxillofacial Pathology
- Entrepreneurship Studies and Influences
- Medical Imaging and Pathology Studies
- Circular RNAs in diseases
- Lung Cancer Diagnosis and Treatment
- Toxin Mechanisms and Immunotoxins
- Genomics, phytochemicals, and oxidative stress
- International Business and FDI
- Firm Innovation and Growth
First Affiliated Hospital of Nanchang University
2012-2024
Nanchang University
2012-2024
Union Hospital
2024
Huazhong University of Science and Technology
2024
Guangdong Polytechnic Normal University
2024
Fuda Cancer Hospital
2023
Moffitt Cancer Center
2020-2021
Tianjin Medical University
2007
Hiring overseas-returned executives is increasingly regarded by researchers and society as an important business strategy. This paper investigates the effects of in top management team on firms China. We propose a mechanism-based framework to study how affect firm innovation. Using listed companies China's manufacturing industry, we find that have positive effect innovation, especially for high-tech firms, large state-owned returned with foreign work experience. Increase research development...
Abstract Background Autophagy has been reported to increase in cancer cells after radiation. However, it remains unknown whether increased autophagy as a result of radiation affects DNA damage repair and sensitizes cells. In this study, the radiosensitization effect rapamycin, mammalian target rapamycin inhibitor that induces autophagy, on human lung adenocarcinoma A549 was investigated. Methods were treated with different concentrations rapamycin. Cell viability evaluated by...
To evaluate the antifungal activity of coptisine, isolated from Coptis chinensis, against Cryptococcus neoformans both in vitro and vivo, along with investigating its underlying mechanism. Microbroth dilution assay disk diffusion were used to coptisine vitro. Scanning electron microscopy (SEM) transmission (TEM) was performed observe changes induced by morphology structural integrity C. cells. Flow cytometry utilized for analysis cell apoptosis. examine if apoptosis includes initial...
Abstract Background Combination CDK4/6 inhibitor and endocrine therapy has been shown to significantly improve progression‐free survival (PFS) in patients with hormone receptor (HR)‐positive, HER2‐negative metastatic breast cancer (mBC). The aim of this retrospective study was evaluate the real‐world benefit first‐line combination cohort correlate treatment efficacy neutropenia, a common toxicity inhibitors. Methods This included HR‐positive, advanced or mBC who were treated palbociclib plus...
It has been proven that cancer cell autophagy can be induced by hypoxia. In addition, was correlated with radiosensitivity. Thus, regulating the signaling pathway is a potential treatment strategy. The aim of this study to investigate effects combined inhibitor 3-methyladenine (3-MA) on radiosensitivity human adenocarcinoma A549 cells in hypoxia condition.A549 were cultured condition, and then divided into two groups: group 3-MA plus group. Electronic microscopy used detect autophagosome...
The diagnosis and treatment of cancer unknown primary site (CUP) present with difficulties produce a poor prognosis. current study presents the case patient CUP in mandibular region was treated docetaxel lobaplatin chemotherapy, vascular embolization tumor. tumor size markedly reduced patient's quality life improved following radiotherapy. report is accompanied by discussion literature to contextualize regimen for patients CUP. These findings will support practices, inform oncologists benefit cancer.
Abstract Background: Combination of a CDK4/6 inhibitor plus endocrine therapy has been shown to significantly improve the progression free survival (PFS) in patients with hormone-receptor (HR)+, HER2- metastatic breast cancer. The aims this retrospective study was: 1) evaluate real-world benefit palbociclib as first line treatment HR+, cancer (mBC) and 2) correlate efficacy combination neutropenia (which is common toxicity inhibitors). Methods: This included advanced mBC who were treated an...