A5100951778- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Cancer-related gene regulation
- Global Energy and Sustainability Research
- Single-cell and spatial transcriptomics
- Esophageal Cancer Research and Treatment
- Insect Utilization and Effects
- Regional Economic and Spatial Analysis
- Biochemical Acid Research Studies
- Gene expression and cancer classification
- Total Knee Arthroplasty Outcomes
- Thermochemical Biomass Conversion Processes
- Urbanization and City Planning
- Oil, Gas, and Environmental Issues
- Optimization and Packing Problems
- Advanced Power Generation Technologies
- Petroleum Processing and Analysis
- Metal Alloys Wear and Properties
- Zeolite Catalysis and Synthesis
- ATP Synthase and ATPases Research
- Diet, Metabolism, and Disease
- Photovoltaic Systems and Sustainability
- Hydrocarbon exploration and reservoir analysis
- Maritime Ports and Logistics
- Iron and Steelmaking Processes
Huaian First People’s Hospital
2024-2025
Hainan University
2024
Xuzhou Medical College
2024
Second People’s Hospital of Huai’an
2024
Shandong University of Technology
2023-2024
Harbin Engineering University
2024
Wuhan University
2024
First Affiliated Hospital of Gannan Medical University
2024
China Medical University
2023
Ecologie Microbienne Lyon
2023
Spatial inequality erodes social cohesion and political stability, impacting global sustainable development human well-being. This study examines spatial in China across economic, social, environmental, infrastructural, innovation dimensions, exploring how these inequalities evolve with economic development. Drawing on the Sustainable Development Goals Chinese planning goals, we selected 13 indicators pertinent to We employed population-weighted coefficient of variation, Gini coefficient,...
N6‑methyladenosine (m6A) serves an essential role in RNA modulation and is implicated multiple malignancies, including colorectal cancer (CRC). Methyltransferase‑like 3 (METTL3) important writer m6A modification, however its CRC modifying small nucleolar host gene 1 (SNHG1), oncogenic long noncoding RNA, remains unclear. In the present study, METTL3 expression was assessed using online bioinformatics analysis, immunohistochemistry staining, western blotting, reverse transcription...
Esophageal squamous cell carcinoma (ESCC), a highly aggressive subtype of esophageal cancer, is characterized by late-stage diagnosis and limited treatment options. Recent advancements in transcriptome sequencing technologies have illuminated the molecular intricacies ESCC tumors, revealing metabolic reprogramming as prominent feature. Specifically, Warburg effect, marked enhanced glycolysis, has emerged hallmark offering potential therapeutic targets. In this study, we comprehensively...
Objective: To explore the relationship of serum levels IL-1β, IL-6, and TNF-α with prosthesis loosening after hip arthroplasty, to establish a predictive model for loosening.Methods: We retrospectively analyzed data 501 patients who underwent arthroplasty in Xi'an International Medical Center Hospital from January 2020 August 2022.Based on radiological diagnosis, were divided into group non-loosening group.Clinical including postoperative inflammatory cytokines collected.Univariant analysis,...
In the present study, antioxidant and anti-human liver cancer (HepG2) cells effects of bioactive peptides from cowhide collagen (BPCC) were evaluated. BPCC exhibited significant scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals ((60.09 ± 3.51)%), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) ((77.40 3.10)%) hydroxyl ((56.00 2.30)%) as well strong reducing power (0.320 0.025). Meanwhile, effectively protected biomacromolecules including proteins, lipids DNA...
Identification of individual-level differentially expressed genes (DEGs) is a pre-step for the analysis disease-specific biological mechanisms and precision medicine. Previous algorithms cannot balance accuracy sufficient statistical power. Herein, RankCompV2, designed identifying population-level DEGs based on relative expression orderings, was adjusted to identify DEGs. Furthermore, an optimized version named as RankCompV2.1, assumption that rank positions differences gene pairs would...
Trilobatin, a glycosylated dihydrochalcone, has been reported to have anti-diabetic properties. However, the underlying mechanism remains unexplained.
BACKGROUND The clinical effects and detailed roles of long non-coding RNA (LncRNA) steroid receptor activator 1 (SRA1) in esophageal squamous cell carcinoma (ESCC) remain ambiguous. In the present study, complementary sites between lncRNA SRA1, miRNA-363-5p, phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) predicted via bioinformatics analysis stimulated us to hypothesize that miRNA-363-5p/LHPP axis might be required for SRA1-mediated ESCC progression. AIM To...
Abstract Background Esophageal Squamous Cell Carcinoma (ESCC) remains a predominant health concern in the world, characterized by high prevalence and mortality rates. Advances single-cell transcriptomics have revolutionized cancer research enabling precise dissection of cellular molecular diversity within tumors. Objective This study aims to elucidate dynamics mechanisms ESCC, focusing on transcriptional influence STAT3 (Signal Transducer Activator Transcription 3) its interaction with LHPP,...
The large equivalent shallow-depth explosion problem is very significant in the field of naval architecture and ocean engineering, as such explosions can be used to attack demolish ships anti-ship missiles. In current work, a refined numerical study flow-field characteristics carried out using self-developed Eulerian finite element solver. Firstly, model validated against theoretical results small test tank. are found agree well with experimental results. next step, cavitation cut-off effect...
Excessive levels of free radicals in the body cause oxidative damage to macromolecules by injuring DNA, proteins, and lipids, which leads structural functional defects ultimately results a number illnesses. The antioxidation trilobatin its inhibitory activity on biological have not been thoroughly investigated. In this research, effects scavenging rates hydroxyl l, 1,1-Diphenyl-2-Picrylhydrazyl (DPPH), 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) as well reducing power were...