- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Ureteral procedures and complications
- Acupuncture Treatment Research Studies
- Enhanced Recovery After Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- Bladder and Urothelial Cancer Treatments
- Neurogenesis and neuroplasticity mechanisms
- Pancreatic and Hepatic Oncology Research
- Neuroscience and Neuropharmacology Research
- Colorectal Cancer Surgical Treatments
- Urinary Bladder and Prostate Research
- Thyroid Disorders and Treatments
- Cancer Cells and Metastasis
- Intracerebral and Subarachnoid Hemorrhage Research
- Pancreatitis Pathology and Treatment
- Angiogenesis and VEGF in Cancer
- Cancer survivorship and care
- Gastric Cancer Management and Outcomes
- Tissue Engineering and Regenerative Medicine
- Nerve injury and regeneration
- Cancer Mechanisms and Therapy
- Radiomics and Machine Learning in Medical Imaging
- Sirtuins and Resveratrol in Medicine
Affiliated Hospital of Jiangsu University
2009-2025
University of South China
2023-2025
Sichuan University
2018-2024
West China Hospital of Sichuan University
2018-2024
Jiangsu University
2007-2024
Guangxi Maternal and Child Health Hospital
2023
Michigan Department of Education
2023
American Urological Association
2023
Creative Commons
2023
Hubei University of Medicine
2023
Abstract Bladder outlet obstruction (BOO) is a prevalent condition arising from urethral stricture, posterior valves, and benign prostatic hyperplasia. Long‐term can lead to bladder remodeling, which characterized by inflammatory cell infiltration, detrusor hypertrophy, fibrosis. Until now, there are no efficacious therapeutic options for BOO‐induced remodeling. Tetrahedral framework nucleic acids (tFNAs) type of novel 3D DNA nanomaterials that possess excellent antifibrotic effects. Here,...
Background/Aims: Neurite outgrowth and synaptogenesis are critical steps for functional recovery after stroke. Resveratrol promotes neurite synaptogenesis, but the underlying mechanism is not well understood, although Sonic hedgehog (Shh) signaling pathway may be involved. Given that resveratrol activates sirtuin (Sirt)1, present study examined whether this mediated by Shh signaling. Methods: Primary cortical neuron cultures were pretreated with drugs before oxygen-glucose...
Alzheimer's disease (AD) is a common human neurodegenerative disorder characterized by progressive deterioration of cognition and memory. Acupuncture at the Baihui (DU20) acupoint has long been used in China to clinically treat cognitive impairment. However, precise mechanism underlying its neuroprotective effects remains be elucidated. In present study, electroacupuncture (EA) was observed markedly ameliorate impairments, reduce aberrant overexpression β‑amyloid(1‑42), inhibit neuronal...
To explore the value of dual-energy computed tomography (DECT) radiomics regional largest short-axis lymph nodes for evaluating node metastasis in patients with rectal cancer.One hundred forty-one cancer (58 LNM+ group, 83 LNM- group) who underwent preoperative total abdominal DECT were divided into a training group and testing (7:3 ratio). After post-processing venous phase images, 120kVp-like images iodine (water) obtained. The highest-risk identified, their long-axis diameter quantitative...
Background/Aims: There is interest in drugs and rehabilitation methods to enhance neurogenesis improve neurological function after brain injury or degeneration. Resveratrol may hippocampal atrophy chronic fatigue mice prenatally stressed rats. However, its effect mechanism of stroke less well understood. Sonic hedgehog (Shh) signaling crucial for the embryonic adult brain, but relatively little known about role Shh resveratrol-enhanced stroke. Methods: Neural stem cells (NSCs) before...
The present study aimed to investigate the mechanisms by which electroacupuncture (EA) ameliorates learning and memory in rats with cerebral ischemic‑reperfusion (I/R) injury. Focal ischemia was induced adult male Sprague‑Dawley (SD) transient middle artery occlusion (MCAO). Following MCAO surgery, received EA at Shenting (DU24) Baihui (DU20) acupoints. results of demonstrated that treatment significantly ameliorated neurological deficits reduced infarct volume (P<0.05). In addition,...
Abstract Objective The aim of this study was to evaluate the feasibility and necessity enhanced recovery after surgery in elderly patients with colorectal cancer by observing inflammatory markers postoperative complications. Methods Hospitalized from Affiliated Hospital Jiangsu University January 2021 September 2022 were included divided into two groups: Enhanced Recovery After Surgery (ERAS) non‐ERAS. Data on complications also collected. Results A total 313 included: 182 ERAS group 131...
AIMTo investigate the role of interferon regulatory factor 5 (IRF5) in reversing polarization lung macrophages during severe acute pancreatitis (SAP) vitro . METHODSA mouse SAP model was established by intraperitoneal (ip) injections 20 μg/kg body weight caerulein.Pathological changes were observed hematoxylin and eosin staining.Lung isolated from bronchoalveolar lavage fluid.The quantity purity detected 9368 November 14, 2016|Volume 22|Issue 42| WJG|www.wjgnet.com
Background and objectives: Enhanced recovery after surgery (ERAS) recommends avoiding enteral nutrition (EN) due to undesirable sequelae such as pulmonary aspiration infections. Not using of EN in nongastric resections under ERAS pathways is often successful. However, parenteral (PN) alone followed by early postoperative oral feeding gastric cancer patients, recommended the guidelines, has unclear benefit only adopted resection. This study aimed compute outcomes PN compared those...
The aim of the present study was to evaluate effect electroacupuncture (EA) on cognitive function following cerebral ischemia‑reperfusion (I/R) injury, and clarify mechanism through which Rho GTPase is associated with EA analgesia modulation dendritic spine plasticity. Rats were randomly divided into three groups: sham surgery group, middle artery occlusion (MCAO) model ischemia MCAO (MCAO+EA) treatment group. MCAO+EA group received at points Baihui (DU20) Shenting (DU24) surgery. It...
Exophiala dermatitidis, a dematiaceous fungus typically found in decaying organic matter worldwide, is rare cause of fungal infections. Cerebral phaeohyphomycosis sporadic but often fatal infection the brain caused by E. dermatitidis. However, due to limited reports, little known about its specific predisposing factors, clinical manifestation, and optimal treatment modality. Here, we report presentation management cerebral Chinese patient. An otherwise healthy, young male who was diagnosed...
The prevention role of Lactiplantibacillus plantarum against the formation kidney stones has been increasingly recognized; its mechanism, however, mainly focused on inhibiting inflammation in colon gastrointestinal (GI) system, and intestinal metabolites from microflora have not revealed fully with regarding to stone formation. In this study, we investigated effect L. J-15 renal calcium oxalate (CaOx) rats induced by ethylene glycol monitored changes their detected 16S rRNA sequencing widely...
Glioblastoma multiforme (GBM) is a complex disease to treat owing its profound chemoresistance. Therefore, we evaluated the combined effect and therapeutic efficacy of temozolomide (TMZ), potent alkylating agent current gold standard therapy for GBM, cryptotanshinone (CTS), which inhibits glioma cell proliferation in GBM cells. Using LN229 U87-MG human cells short-term stimulation vitro model, cytotoxic anti-proliferative effects single treatment with 4 μM CTS 200 TMZ were investigated....
The aim of the present study was to investigate effect electroacupuncture (EA) on cognitive deficits, and underlying mechanism following cerebral ischemia‑reperfusion (I/R) via calmodulin (CaM)‑calmodulin‑dependent protein kinase type IV (CaMKIV)‑cyclic adenosine monophosphate response elements binding (CREB) intracellular signaling pathway in hippocampus. In total, 45 adult female Sprague‑Dawley rats were randomly divided into three groups, namely sham group, middle artery occlusion (MCAO)...
To outline our step-by-step technique for the endoscopic treatment of ureteric stricture.Between January 2019 and June 2020, 25 patients with strictures underwent bypass were included in this study. The surgery three key steps. First, holmium laser endoureterotomy was used to establish a small channel. Then, balloon dilatation performed create large Finally, an Allium stent inserted.Over median follow-up time 12 months, success rate 92.0% (23/25). operating 78 min. incidence pain 16% (4/25),...
新型 2-氰基丙烯酸酯(酰胺)类衍生物的设计合成及杀线虫活性研究 王