A5053523491- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple and Secondary Primary Cancers
- Inflammatory Biomarkers in Disease Prognosis
The People's Hospital of Guangxi Zhuang Autonomous Region
2024
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had and continues to have a significant impact on global public health. One of characteristics is surface homotrimeric spike protein, which primarily responsible for host immune response upon infection. Here we present preclinical studies broadly protective subunit vaccine developed from our trimer domain platform using Delta antigen design through purification, evaluation manufacturability. pre-fusion trimerized PF-D-Trimer, was...
Abstract The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had and still a considerable impact on global public health. One of characteristics is surface homotrimeric spike protein, primary responsible for host immune response upon infection. Here we show preclinical studies broad protective subunit vaccine developed from our Trimer Domain platform using Delta antigen design to purification, evaluation manufacturability. prefusion trimerized PF-D-Trimer, was highly expressed in...