Yan Xu

ORCID: 0000-0001-6930-0093
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Atherosclerosis and Cardiovascular Diseases
  • T-cell and B-cell Immunology
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Immune Cell Function and Interaction
  • Microbial Metabolic Engineering and Bioproduction
  • Anaerobic Digestion and Biogas Production
  • Long-Term Effects of COVID-19
  • Phagocytosis and Immune Regulation
  • Sustainable Supply Chain Management
  • Building Energy and Comfort Optimization
  • Endoplasmic Reticulum Stress and Disease
  • Ferroptosis and cancer prognosis
  • Environmental Sustainability in Business
  • Infrastructure Maintenance and Monitoring
  • Advanced Antenna and Metasurface Technologies
  • Construction Engineering and Safety
  • Power Systems and Technologies
  • Monoclonal and Polyclonal Antibodies Research
  • Antenna Design and Analysis
  • SARS-CoV-2 detection and testing
  • COVID-19 epidemiological studies
  • Wireless Sensor Networks and IoT

Wuhan YZY Biopharma (China)
2022-2024

Zhuhai People's Hospital
2022-2023

Jinan University
2022-2023

Henan Normal University
2023

Xi'an Jiaotong University
2023

Jilin University
2023

Beijing University of Chinese Medicine
2022

Jiaxing University
2022

Shaoxing People's Hospital
2022

Shaanxi University of Science and Technology
2019

Atherosclerosis (AS) is widespread and develops into circulatory system problems. T cells play an essential regulatory role in AS occurrence development. So far, there no bibliometric research on AS. To learn more about cell development, 4,381 records were retrieved from Web of Science™ Core Collection. Then, these scientometrically analyzed using CiteSpace VOSviewer terms spatiotemporal distribution, author subject categories, topic references, keywords. Our analysis provides basic...

10.3389/fimmu.2022.948314 article EN cc-by Frontiers in Immunology 2022-10-13

To analyse the research progress and frontier dynamics of green supply chain management, this paper uses Web Science’s citation database to search filter related documents from 2007–2018. A total 1391 articles were obtained. On basis, a bibliometric analysis method was utilized study literature characteristics hotspots management research. Our results show following: (1) The current amount published on field is exponentially increasing. Research tended develop after 2013. (2) has not formed...

10.3390/su11123459 article EN Sustainability 2019-06-24

Ageing is often accompanied with a decline in immune system function, resulting ageing. Numerous studies have focussed on the changes different lymphocyte subsets diseases and immunosenescence. The change phenotype key indication of diseased or healthy status. However, number brought about by ageing not been comprehensively analysed. Here, we analysed T natural killer (NK) cell subsets, differentiation states 43,096 individuals, aged 20-88 years, without known diseases. Thirty-six parameters...

10.1007/s43657-023-00106-0 article EN cc-by Phenomics 2023-05-23

The global community has been affected by the coronavirus disease 2019 (COVID-19), which emerged in December 2019. Since then, many studies have conducted on cardiovascular diseases (CVDs) and COVID-19. aim of this study was to perform a bibliometric visual analysis published relationship between CVDs COVID-19.1,890 publications were retrieved from Web Science Core Collection database January 5, 2022. Microsoft Office Excel CiteSpace then used carry out scientometric relevant literature...

10.3389/fpubh.2022.1022810 article EN cc-by Frontiers in Public Health 2022-12-08

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had and continues to have a significant impact on global public health. One of characteristics is surface homotrimeric spike protein, which primarily responsible for host immune response upon infection. Here we present preclinical studies broadly protective subunit vaccine developed from our trimer domain platform using Delta antigen design through purification, evaluation manufacturability. pre-fusion trimerized PF-D-Trimer, was...

10.1038/s41541-023-00636-8 article EN cc-by npj Vaccines 2023-03-15

In the United States, coronavirus disease 2019 (COVID-19) cases have consistently been linked to prevailing variant XBB.1.5 of SARS-CoV-2 since late 2022. A system has developed for producing and infecting cells with a pseudovirus (PsV) investigate infection in Biosafety Level 2 (BSL-2) laboratory. This utilizes lentiviral vector carrying ZsGreen1 Firefly luciferase (Fluc) dual reporter genes, facilitating analysis experimental results. addition, we created panel PsV variants that depict...

10.1016/j.heliyon.2024.e29939 article EN cc-by-nc-nd Heliyon 2024-04-01

Spleen tyrosine kinase (Syk) is an intracellular involved in the signal transduction immune cells mainly. Its aberrant regulation associated with diversified allergic disorders, autoimmune diseases and B cell malignancies. Therefore, inhibition of Syk considered a reasonable approach to treat autoimmune/inflammatory Here we described preclinical characterization sovleplenib (HMPL-523), novel, highly potent selective, oral inhibitor, several rodent disease models. Sovleplenib potently...

10.1124/jpet.123.001752 article EN Journal of Pharmacology and Experimental Therapeutics 2023-11-02

Coronary atherosclerotic heart disease (CAD) is a chronic inflammatory cardiovascular with high morbidity and mortality. Growing data indicate that many immune cells are involved in the development of atherosclerosis. However, immunological roles γδ T initiation progression CAD not fully understood. Here, we used flow cytometry to determine phenotypical changes their subpopulations peripheral blood samples collected from 37 patients. The Pearson correlation coefficient was analyze...

10.3389/fimmu.2022.900334 article EN cc-by Frontiers in Immunology 2022-07-08

23,037 values of concrete compressive strength from construction sites were obtained Beijing Building Construction Research Institute 2009-2012 by standard cubes testing method. The mean values, deviations, coefficients variations, maxima and minima derived the original analyzed compared with data in 1989. results make up for lack C25/C30 maxima/minima every class former data. Both variations have increased recent years. log-normal distribution commonly used statistics is not that suitable...

10.4028/www.scientific.net/amr.671-674.1641 article EN Advanced materials research 2013-03-01

10.23919/aces-china60289.2023.10249374 article EN 2023-08-15

Abstract The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had and still a considerable impact on global public health. One of characteristics is surface homotrimeric spike protein, primary responsible for host immune response upon infection. Here we show preclinical studies broad protective subunit vaccine developed from our Trimer Domain platform using Delta antigen design to purification, evaluation manufacturability. prefusion trimerized PF-D-Trimer, was highly expressed in...

10.1101/2022.09.26.509414 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2022-09-26
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