Mengzhuo Yin

ORCID: 0000-0003-1517-3134
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About
Contact & Profiles
Research Areas
  • Atherosclerosis and Cardiovascular Diseases
  • Immune Cell Function and Interaction
  • Circular RNAs in diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Autoimmune Neurological Disorders and Treatments
  • T-cell and B-cell Immunology
  • RNA regulation and disease
  • Cholesterol and Lipid Metabolism
  • Immune cells in cancer
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Lymphoma Diagnosis and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiac tumors and thrombi

Guangzhou Medical University
2021-2024

Guangzhou First People's Hospital
2021-2024

South China University of Technology
2021-2024

Southern Medical University
2021

Nanfang Hospital
2021

Atherosclerosis is a lipid-driven chronic inflammatory disease in which lipid-laden macrophage foam cells lead to inflamed lesions arteries. Previous studies have proven that sulfotransferase 2B1b (SULT2B1b) has several roles the regulation of lipid metabolism and response. However, little known about functions SULT2B1b ox-LDL-induced inflammation macrophages. In this study, after treatment with either ox-LDL alone or combined transfection siRNAs targeting SULT2B1b, IL-6, TNF-α, NF-κB, IKKβ...

10.18632/aging.202273 article EN cc-by Aging 2021-01-10

Background Disruption of the blood–brain barrier (BBB) is an important pathophysiological process anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. A recent multi-center study showed that soluble (s) CD146 a potential biomarker for monitoring early BBB damage and central nervous system inflammation, but little known about sCD146 in anti-NMDAR Method Twenty-three encephalitis patients seventeen controls with non-inflammatory neurological diseases were recruited. inflammatory...

10.3389/fimmu.2021.680424 article EN cc-by Frontiers in Immunology 2021-06-16

Coronary atherosclerotic heart disease (CAD) is a chronic inflammatory cardiovascular with high morbidity and mortality. Growing data indicate that many immune cells are involved in the development of atherosclerosis. However, immunological roles γδ T initiation progression CAD not fully understood. Here, we used flow cytometry to determine phenotypical changes their subpopulations peripheral blood samples collected from 37 patients. The Pearson correlation coefficient was analyze...

10.3389/fimmu.2022.900334 article EN cc-by Frontiers in Immunology 2022-07-08

We aim to investigate cardiovascular mortality risk among diffuse large B-cell lymphoma (DLBCL) patients and explore trends in the past decades United States. extracted data from Surveillance, Epidemiology, End Results database for adult diagnosed with DLBCL between 1975 2019. Standardized ratio, joinpoint regression analysis, competing model were analyzed. Overall, 49,918 enrolled, of whom 4167 (8.3%) deaths observed, which was 1.22 times number expected (95%CI, 1.19–1.26). During...

10.1080/10428194.2024.2364830 article EN Leukemia & lymphoma/Leukemia and lymphoma 2024-06-11
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