A5101672608- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- COVID-19 and Mental Health
- Child Abuse and Trauma
- Advanced MRI Techniques and Applications
- Noise Effects and Management
- Vehicle Noise and Vibration Control
- Healthcare and Venom Research
- Rheumatoid Arthritis Research and Therapies
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Migration, Health and Trauma
- Platelet Disorders and Treatments
- Acoustic Wave Phenomena Research
- Tendon Structure and Treatment
- Heart Rate Variability and Autonomic Control
- Neural dynamics and brain function
- Stroke Rehabilitation and Recovery
- Chronic Lymphocytic Leukemia Research
- Botulinum Toxin and Related Neurological Disorders
- Mast cells and histamine
- Hip and Femur Fractures
Chengdu University of Traditional Chinese Medicine
2022-2025
Guangdong University of Technology
2023-2024
Second Xiangya Hospital of Central South University
2018-2023
Central South University
2018-2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023
Chongqing Medical University
2023
Zhejiang Chinese Medical University
2020-2022
Huazhong University of Science and Technology
2022
Union Hospital
2022
Yang Hospital
2021
Abstract The multilayer dynamic network model has been proposed as an effective method to understand the brain function. In particular, derived from definition of clustering coefficient in static networks, temporal provides a direct measure topological stability networks and shows potential predicting altered functions. However, test–retest reliability demographic‐related effects on this remain be evaluated. Using data set Human Connectome Project (157 male 180 female healthy adults; 22–37...
Osteoarthritis (OA) is a chronic degenerative joint disease, related to the overexpression of matrix metalloproteinases (MMPs), disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), inflammation, chondrocyte apoptosis. Nesfatin-1 an adipokine, which plays important role in development OA, especially obese people. In present study, cartilage degradation apoptosis observed OA patients was evaluated. Furthermore, anti-inflammatory anti-apoptotic effects nesfatin-1, its...
The COVID-19 pandemic has increased psychological stress among adolescents, and the relation between perceived (PS) psychotic-like experiences (PLEs) been well-established. However, little is known about role of family functioning (FF) in this relation, especially when adolescents experienced extended lockdown period with members.A total 4807 completed retrospective paper-and-pencil survey after school reopening May 14th June 6th, 2020 Hunan Province, China. We measured PS Perceived scale...
This study performed a repeated cross-sectional analysis to explore possible trends in mental health problems among Chinese adolescents over the years of 2016–2020. A total 2,837 different seventh-grade students were surveyed three waves from junior high school Changsha city, Hunan province China (978 2016, 949 2019, and 910 2020) using Mental Health Inventory Middle School Students (MMHI-60). The results showed that obsessive-compulsive tendencies, interpersonal sensitivity, depression,...
Abstract Diabetes mellitus (DM) is one of the prominent risk factors for pathological development and progression tendinopathy. One feature DM‐related changes in tendinopathy accumulation advanced glycation end products (AGEs) affected tendons. Pioglitazone (Pio), a peroxisome proliferator‐activated receptor γ agonist, performs protective effect against AGEs. The present study aimed to investigate pathogenetic role AGEs on tendon‐derived stem cells (TDSCs) determine Pio AGEs‐induced TDSC...
Osteoarthritis (OA) is the most prevalent joint disease and uncontrolled inflammation now recognized to play vital roles in OA development. The orphan nuclear receptor 4A1(NR4A1) a key negative regulator of inflammatory responses but its role osteoarthritis remains unclear. In present study, we found that NR4A1 expression was elevated human cartilage vitro model, which could be blocked by NF-κB signal inhibitor JSH23. overexpression inhibited, whereas knockdown enhanced IL-1β induced COX-2,...
Tendinopathy is a common musculoskeletal disorder, mainly affects the athletes and aged people. Tumor necrosis factor-α (TNF-α) plays an initiator role in tendinopathy. Tectorigenin extract component of Belam-canda Chinesis, which performs anti-inflammatory anti-apoptosis effects. The present study stablished to investigate tectorigenin against pathogenetic effects TNF-α on tendon-derived stem cells (TDSCs) vivo vitro. findings indicated that able induce TDSC inflammation, apoptosis...
Overprotection and overcontrol from parents or other family members, which are not rare in the Chinese culture, have been suggested to be traumatic experiences for some children. However, research on overprotection/overcontrol is much rarer China compared with childhood trauma subtypes. One of possible reasons this lack easy feasible screening tools. In study, we therefore translated validated a version 33-item Childhood Trauma Questionnaire (CTQ-33), was expanded widely-used 28-item CTQ an...
Introduction This study aimed to investigate the possible associations between problematic smartphone use and brain functions in terms of both static dynamic functional connectivity patterns. Materials methods Resting-state magnetic resonance imaging data were scanned from 53 young healthy adults, all whom completed Short Version Smartphone Addiction Scale (SAS-SV) assess their severity. Both network measures evaluated for each participant. The correlated SAS-SV scores, compared participants...
Many studies have reported an association between childhood trauma exposure and schizophrenia. Among these studies, the Short-form Childhood Trauma Questionnaire (CTQ-SF) is one of most widely used measures trauma. However, little known regarding long-term reliability CTQ-SF, especially in patients with psychopathology.The CTQ-SF was administered to 50 diagnosed schizophrenia from a hospital Changsha, Hunan, China. These were asked re-complete when they re-hospitalized or received outpatient...
Major depressive disorder (MDD) is a common psychiatric which associated with an accelerated biological aging. However, little known whether such process would be reflected by more rapid aging of the brain function. In this study, we tested hypothesis that MDD characterized brain’s default-mode network (DMN) functions. Resting-state functional magnetic resonance imaging data 971 patients and 902 healthy controls (HCs) was analyzed, drawn from publicly accessible, multicenter dataset in...
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by deterioration of articular cartilage. Dual specificity phosphatase 5 (DUSP5), member the DUSP subfamily, known to regulate cellular inflammation. Here, we studied relationship between DUSP5 and OA knockdown overexpression DUSP5, respectively. Results from in vitro experiments demonstrated that increased interleukin-1β (IL-1β)-induced expression inflammatory genes, such as inducible nitric oxide synthase (iNOS),...