A5083562688- Advanced Multi-Objective Optimization Algorithms
- interferon and immune responses
- Nerve injury and regeneration
- Anesthesia and Neurotoxicity Research
- Neuropeptides and Animal Physiology
- Neurogenesis and neuroplasticity mechanisms
- Pluripotent Stem Cells Research
- Pain Mechanisms and Treatments
- Sphingolipid Metabolism and Signaling
- Endoplasmic Reticulum Stress and Disease
- Genomics and Phylogenetic Studies
- Pesticide Exposure and Toxicity
- Risk and Portfolio Optimization
- Cytokine Signaling Pathways and Interactions
- CRISPR and Genetic Engineering
- X-ray Diffraction in Crystallography
- Intramuscular injections and effects
- Optimization and Mathematical Programming
- Single-cell and spatial transcriptomics
- Parasite Biology and Host Interactions
- Pesticide and Herbicide Environmental Studies
- Cerebrovascular and Carotid Artery Diseases
- Carbohydrate Chemistry and Synthesis
- Nanoparticle-Based Drug Delivery
- Protein Kinase Regulation and GTPase Signaling
Xiamen University
2024
Cold Spring Harbor Laboratory
2024
Central South University
2024
Biogen (United States)
2004-2021
Shandong University
2011-2014
College of Marin
2011
Changshu No.1 People's Hospital
2010
Soochow University
2010
Taipei Medical University
2002
Boston Children's Hospital
2001
Many central nervous system regions at all stages of life contain neural stem cells (NSCs). We explored how these disparate NSC pools might emerge. A traceable clone human NSCs was implanted intraventricularly to allow its integration into cerebral germinal zones Old World monkey fetuses. The distributed two subpopulations: One contributed corticogenesis by migrating along radial glia temporally appropriate layers the cortical plate and differentiating lamina-appropriate neurons or glia;...
Stroke is the second leading cause of death and disability worldwide. However, how prevalence stroke varies across world uncertain.
S1P5 is one of the five sphingosine-1-phosphate (S1P) receptors which play important roles in immune and CNS cell homeostasis, growth, differentiation. Little known about effect modulation due to lack specific modulators with suitable druglike properties. Here we describe discovery optimization a novel series potent selective antagonists identification an orally active brain-penetrant tool compound 15.
Two new organophosphorus pesticides, analog compounds of chlorpyrifos and phoxim, were prepared evaluated in terms acute oral toxicity to SD rats insecticidal activity against different insects the laboratory. The two showed similar corresponding pesticides but with higher activity.
Worst-case robust optimization problem is concerned with finding a candidate solution that insensitive to uncertainty. This involves nested-loop structure based on the worst-case analysis, it an expensive which has large computational complexity. paper presents method of reduced Firstly, state transition algorithm (STA) utilized explore and exploit solutions search space. Then, adaptive incremental Kriging (IKriging) metamodel proposed replace evaluation functions for evaluating robustness...
Objective To evaluate the effects of dopamine (DA) and norepinephrine (NE) on hemodynamics oxygen metabolism tissue in patients with septic shock. Methods Forty sixty shock after abdominal surgery were assigned to groups DA NE randomly. They given or for 6 hours. Heart rate (HR), mean artery pressure (MAP), cardiac index (CI), stroke (SI), systemic vascular resistance (SVRI), mixed venous saturation (SvO2), early lactate clearance, urine volume per hour (UV) measured at end treatment....
Objective To explore the impact of different doses tetanus antitoxin(TAT) skin test on results judgment and safety two desensitization injection methods. Methods 276 patients who needed TAT were randomly divided into experimental group control group. Each included 138 patients. The former followed specifications provided by pharmaceutical companies while latter textbook instructions.Results 5 positive cases (3.76%) reported 14 ( 10. 14% ) group, with statistical significance (P ＜0. 05). No...