A5101497754- Lipoproteins and Cardiovascular Health
- Lung Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Metabolomics and Mass Spectrometry Studies
- Protein Kinase Regulation and GTPase Signaling
- Nutrition, Genetics, and Disease
- Mitochondrial Function and Pathology
- Healthcare cost, quality, practices
- Lipid metabolism and disorders
- Ion channel regulation and function
- Yersinia bacterium, plague, ectoparasites research
- Liver Diseases and Immunity
- Takotsubo Cardiomyopathy and Associated Phenomena
- Thyroid Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Infant Health and Development
- Respiratory and Cough-Related Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Immunodeficiency and Autoimmune Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diabetes Treatment and Management
- Protease and Inhibitor Mechanisms
- Cancer, Lipids, and Metabolism
Odense University Hospital
1995-2024
Svendborg Sygehus
2016
University of Southern Denmark
2006
Dansk Sygehus Institut
1994
Abstract Background Malignant pleural effusion (MPE) is a common and debilitating condition seen in advanced cancer disease, life-expectancy short. Symptoms include pain severe shortness of breath. Current first-line treatment options drainage using catheters as well pleurodesis. However, these modalities are often inefficient patients need repeated procedures. Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) minimally invasive procedure, where antineoplastic agents nebulized under...
Abstract Familial defective apolipoprotein B (FDB) is a clinical condition resembling familial hypercholesterolemia. The underlying genetic defects are mutations in the B-100 (apo B-100) gene. Two (Arg3500 --> Gln and Arg3531 Cys) known to date. We designed denaturing gradient-gel electrophoresis (DGGE) technique detect sequence variations codons 3456-3553 of apo In 46 heterozygous FDB patients with predominant codon 3500 mutation, uniform four-band DGGE pattern was seen, whereas 57...
Summary Understanding of the aetiological basis thyroid autoimmunity may be gained by studying early stages disease process. We aimed to (1) investigate relationship between antibody status and Yersinia enterocolitica (YE) infection in euthyroid subjects (2) explore relative importance genetic environmental risk factors acquisition YE infection. The association was explored using a case–control design. Furthermore, antibody-positive twins were compared with their antibody-negative co-twin....
Abstract Objectives Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) is a minimally invasive cancer-directed therapy for patients with malignant pleural effusion (MPE) and/or metastasis (PLM). PITAC based on IntraPeritoneal Chemotherapy, which has proven to be safe and feasible. Since 2012, 47 PITACs have been published, prospective data feasibility, safety potential local response are lacking. Methods The prospective, controlled, phase-I study designed treat MPE PITAC. There no...
Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) has been suggested as a new therapy for patients with malignant pleural effusion (MPE) and/or metastasis (PLM). The have poor prognosis median survival of 3 to 12 months. We present feasibility, patient safety, and cytological/histological response assessment in PITAC-treated MPE PLM.