About
Contact & Profiles
A5114221789
Research Areas
- DNA Repair Mechanisms
- Genetics, Aging, and Longevity in Model Organisms
- Genetics and Neurodevelopmental Disorders
- Ubiquitin and proteasome pathways
- RNA Research and Splicing
State Key Laboratory of Medicinal Chemical Biology
2023-2024
Nankai University
2023-2024
During meiosis, cohesin and meiosis-specific proteins organize chromatin into an axis-loop architecture, coordinating homologous synapsis, recombination, ordered chromosome segregation. However, how the meiotic axis is assembled differentiated with progression remains elusive. Here, we explore dynamic recruitment of two long arms bivalent proteins, LAB-1 LAB-2, in Caenorhabditis elegans. LAB directly interact core HORMA complexes weak interactions contribute to their recruitment. phase...
10.1083/jcb.202212035
article
EN
cc-by-nc-sa
The Journal of Cell Biology
2023-11-27
10.1038/s41418-024-01375-6
article
EN
Cell Death and Differentiation
2024-09-05
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